发育性髋脱位围术期输血与HGB、PLT、HCT水平的相关性分析  

Correlation analysis of perioperative blood transfusion with serum HGB,PLT and HCT levels after developmental dislocation of the hip

作　　者：王峻 葛艳玲[1] 王默然 韩晨曦 李星晨[1] 王小捷 WANG Jun;GE Yan-ling;WANG Mo-ran;HAN Chen-xi;LI Xing-chen;WANG Xiao-jie(Department of Blood Transfusion,Beijing Jishuitan Hospital,Beijing 100035,China)

机构地区：[1]北京积水潭医院输血科,北京100035

出　　处：《河北医科大学学报》2023年第12期1427-1431,共5页Journal of Hebei Medical University

基　　金：北京市自然科学基金(7192222)。

摘　　要：目的研究发育性髋脱位围术期输血与血红蛋白(hemoglobin,HGB)、血小板计数(platelet count,PLT)、血细胞比容(hematocrit,HCT)的相关性。方法回顾性分析我院行发育性髋脱位术患儿84例的临床资料。根据患儿围术期输血情况分为输血组(n=50)和非输血组(n=34)。比较2组性别、年龄、体重、患侧、Tonnis分级、手术时间及HGB、PLT、HCT差异。通过受试者工作特征(receiver operating characteristic,ROC)曲线分析HGB、PLT、HCT预测发育性髋脱位围术期输血的价值,最后通过多因素Logistic回归分析发育性髋脱位围术期输血的影响因素。结果2组性别构成比、年龄、体重、患侧构成比、Tonnis分级构成比、手术时间比较差异无统计学意义(P>0.05);输血组HGB、PLT、HCT水平显著低于非输血组,差异有统计学意义(P<0.05)。经ROC分析证实HGB、PLT、HCT及联合检测均能用于发育性髋脱位围术期输血的预测,曲线下面积分别为0.714、0.852、0.858、0.894(P<0.05)。经多因素Logistic回归分析证实,HGB、PLT、HCT为发育性髋脱位围术期输血的影响因素(P<0.05)。结论发育性髋脱位围术期具有较高的输血发生率,输血的发生受到HGB、PLT、HCT水平降低等因素影响,临床医师应当予以密切关注。Objective To study the correlation of perioperative blood transfusion with hemoglobin(HGB),platelet count(PLT)and hematocrit(HCT)after developmental dislocation of the hip(DDH).Methods The clinical data of 84 children undergoing surgery for DDH in our hospital were retrospectively analyzed.Blood transfusion in children during perioperative period was recorded.The children undergoing blood transfusion were set as the blood transfusion group(n=50),and the children without undergoing blood transfusion were set as the non-transfusion group(n=34).The gender,age,body weight,the affected side,Tonnis grade,duration of operation,and differences in HGB,PLT,and HCT were compared between two groups.Receiver operating characteristic(ROC)curve was used to analyze the value of HGB,PLT,and HCT in predicting perioperative blood transfusion for DDH.Ultimately,multivariate Logistic regression was used to analyze the influencing factors of perioperative blood transfusion for DDH.Results There was no significant difference in gender composition ratio,age,body weight,affected side composition ratio,Tonnis grade composition ratio,and duration of operation between two groups(P>0.05).The levels of HGB,PLT and HCT in the blood transfusion group were significantly lower in the non-transfusion group,and the difference was statistically significant(P<0.05).ROC analysis confirmed that HGB,PLT HCT and joint testing could be used to predict perioperative blood transfusion for DDH,and the area under the ROC curve(AUC)was 0.714,0.852,0.858 and 0.894,respectively(P<0.05).Multivariate Logistic regression analysis confirmed that HGB,PLT,and HCT were the influencing factors of perioperative blood transfusion for DDH(P<0.05).Conclusion There is a high incidence of blood transfusion in the perioperative period of DDH.The incidence of blood transfusion is affected by the reduction of HGB,PLT,HCT and other factors,which warrants close attention of clinicians.

关 键 词：髋脱位 输血 血小板计数 血红蛋白 红细胞比容 

分 类 号：R684.7[医药卫生—骨科学]