探讨全血H-FABP床旁快检在AMI诊断应用价值  

To explore the application value of whole-blood H-FABPby POCT in AMI diagnosis

作　　者：谭琴 Tan Qin(Wanzhou District Shanghai Hospital,The Laboratory Medicine,Chongqing Wanzhou,404100,China)

机构地区：[1]万州区上海医院检验科,重庆万州404100

出　　处：《现代科学仪器》2023年第6期42-44,共3页Modern Scientific Instruments

摘　　要：目的:探讨床旁快检全血心型脂肪酸结合蛋白(H-FABP)在急性心肌梗死(AMI)诊断应用价值。方法:用床旁快速检测方法对AMI患者和非致命性的、非心源性急诊胸痛患者的全血H-FABP、全血MYO(肌红蛋白)和全血CK-MB(肌酸激酶同工酶)水平检测并比较分析。结果:实验组全血H-FABP、MYO和CK-MB水平均高于对照组,H-FABP是AMI发病的独立影响因素,与MYO和CK-MB联检对AMI诊断的AUC、准确度、灵敏度等均高于单独检测。结论:全血H-FABP是AMI发病的独立影响因素,床旁快检该指标在AMI早期诊断中有较高的应用价值,联合全血MYO和CK-MB检测可进一步提高对AMI诊断的价值。objective:To explore the application value of whole-blood cardiac fatty acid-binding protein(H-FABP)in the diagnosis of acute myocardial infarction(AMI).Methods:Whole Blood H-FABP,whole blood MYO,and whole blood CK-MB were measured and analyzed in AMI patients and non-fatal,non-cardiac emergency chest pain patients by rapid bedside Myoglobin assay.Results:The levels of H-FABP,MYO and CK-MB in the experimental group were higher than those in the control group,H-FABP is an independent factor affecting the pathogenesis of AMI,and the AUC,accuracy and sensitivity of AMI diagnosis with MYO and CK-MB were higher than those in the individual detection.Conclusion:Whole Blood H-FABP is an independent risk factor for AMI.Bedside rapid detection of H-FABP has a high value in the early diagnosis of AMI.Combined detection of whole blood MYO and CK-MB can further improve the diagnostic value of AMI.

关 键 词：急性心肌梗死 床旁快速检测 心型脂肪酸结合蛋白 检测水平 

分 类 号：R446[医药卫生—诊断学]