SIRS、PNI和mHLA-DR%预测脓毒症预后  

Predictive of SIRS,PNI and mHLA-DR%for prognosis in sepsis

作　　者：王标 李霞[1] 丁颖楠 武亚娟 Wang Biao;Li Xia;Ding Yingnan;Wu Yajuan(Department of Critical Care,Dongcheng Hospital,First Affiliated Hospital of Anhui Medical University,Hefei 231600,Anhui Province)

机构地区：[1]安徽医科大学第一附属医院东城院区重症医学科,安徽合肥231600

出　　处：《现代科学仪器》2023年第6期58-61,共4页Modern Scientific Instruments

摘　　要：目的:分析全身炎症反应综合征(SIRS)评分、预后营养指数(PNI)与单核细胞人类白细胞抗原(mHLA-DR)%对脓毒症患者预后的预测价值。方法:选择2020年1月至2022年12月就诊于本院的脓毒症患者根据其28d生存结局分为死亡组和存活组。分析影响脓毒症预后的危险因素及其对预后的预测价值。结果:死亡组SIRS显著高于存活组(P<0.05),PNI、mHLA-DR%显著低于存活组(P<0.05);SIRS升高、PNI和mHLA-DR%下降为脓毒症患者预后的危险因素;SIRS、PNI、mHLA-DR%和联合检测的ROC曲线下面积为0.753、0.792、0.705、0.930。结论:SIRS、PNI和mHLA-DR%为影响脓毒症患者预后的危险因素可以对预后结局进行预测。Objective:To analyze the predictive value of systemic inflammatory response syndrome(SIRS),prognostic nutritional index(PNI),and monocytic human leukocyte antigen DR(mHLA-DR)%for prognosis in patients with sepsis.Methods:Patients with sepsis treated in the hospital were enrolled between January 2020 and December 2022.According to survival status at 28d after admission,they were divided into death group and survival group.The risk factors of prognosis and predictive value of risk factors in sepsis patients were analyzed.Results:SIRS in death group were significantly higher than those in survival group(P<0.05),while PNI and mHLA-DR% were significantly lower than those in survival group(P<0.05).SIRS,PNI and mHLA-DR% were influencing factors of prognosis.ROC curves analysis showed that area under the curve of SIRS score,PNI,mHLA-DR percentage and combined detection were(0.753,0.792,0.705,0.930)respectively.Conclusion:SIRS,PNI,and mHLA-DR% are risk factors that can predict the prognosis of sepsis patients.

关 键 词：脓毒症 预后营养指数 血清降钙素原 单核细胞人类白细胞抗原 

分 类 号：R631.3[医药卫生—外科学]