七氟醚对老年股骨粗隆间骨折患者围术期Th1/Th2平衡的影响  

Effect of sevoflurane on perioperative Th1/Th2 balance in elderly patients with intertrochanteric femoral fractures

作　　者：李林 王炜林 Li Lin;Wang Weilin(Department of Anesthesiology,Fuyang Women's and Children's Hospital,Fuyang,236030,Anhui,China)

机构地区：[1]阜阳市妇女儿童医院麻醉科,安徽阜阳236030

出　　处：《现代科学仪器》2023年第6期85-88,共4页Modern Scientific Instruments

摘　　要：目的:探讨七氟醚对老年股骨粗隆间骨折患者围术期Th1/Th2平衡的影响。方法:选取91例老年股骨粗隆间骨折患者分为A、B两组,对比麻醉前后Th1/Th2变化。结果:两组SBP、DBP时间、交互作用、Th1、Th2、Th1/Th2、血清IFN-γ、IL-4水平组间、时间、交互作用对比差异均有统计学意义(P<0.05);A组住院时间较短,恶心呕吐发生率较低(P<0.05)。结论:七氟醚麻醉可控制患者的Th1/Th2紊乱,减少恶心呕吐,还可以降低住院时间。Objective:To investigate the effect of sevoflurane on the perioperative Th1/Th2 balance in elderly patients with intertrochanteric femoral fractures.Methods:Ninety-one elderly patients with intertrochanteric femur fracture were selected and divided into two groups A and B.The Th1/Th2 changes were compared before and after anaesthesia.Results:The differences in SBP,DBP time,interaction,Th1,Th2,Th1/Th2,serum IFN-γ and IL-4 levels between the two groups,time and interaction were statistically significant(P<0.05);Group A had a shorter hospital stay and a lower incidence of nausea and vomiting(P<0.05).Conclusion:Sevoflurane anaesthesia controls the patient's Th1/Th2 disorder,reduces nausea and vomiting,and also reduces the length of hospital stay..

关 键 词：七氟醚 老年 股骨粗隆间骨折 围术期 T辅助细胞 

分 类 号：R614.1[医药卫生—麻醉学]