体内剂量测量EPIgray系统的验收测试及临床应用评估  

Acceptance testing and clinical assessment of the in-vivo dose measurement EPIgray system

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作  者:蒋徐铭 贺晓东 沈文同[1] 陈佳艺[1] 李敏[1] 张毅斌[1] JIANG Xu-ming;HE Xiao-dong;SHEN Wen-tong(Department of Radiotherapy,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;不详)

机构地区:[1]上海交通大学医学院附属瑞金医院放射治疗科,上海200025

出  处:《中国医学装备》2023年第12期26-32,共7页China Medical Equipment

摘  要:目的:通过验收测试评估调强放射治疗(IMRT)及容积旋转调强治疗(VMAT)中在体剂量验证系统EPIgray剂量重建的准确度,并进行初步的临床应用。方法:选择医院收治的37例不同部位癌症患者病例进行临床测试,参考厂家提供的验收手册以及美国医学物理师协会(AAPM)TG-119报告的建议,采用方野、条带野和调强计划在模体上测试EPIgray系统的剂量重建精度。通过改变均匀模体厚度及照射源皮距来研究系统对误差的识别能力。对37例VMAT的不同部位癌症患者进行临床测试,分析EPIgray系统剂量重建与治疗计划系统计算剂量的一致性。结果:方野测试中EPIgray剂量重建有良好的线性且重建精度较高,在不同大小的射野不同厚度的模体上射野中心轴的剂量重建精度最高为(0.10±0.39)%,在离轴和深度方向上除剂量建成区和射野边缘外剂量重建精度均在3.0%以内。在IMRT以及VMAT计划测试中剂量重建偏差均<5.0%。随着计划复杂度以及模体异质性的增加重建精度略有下降,但剂量重建偏差均在允许偏差范围内。37例患者临床测试中处方剂量点的平均重建偏差为(-0.6±4.8)%,靶区范围内的采样点平均偏差为(-2.1±2.7)%。在射野外及剂量梯度大的区域重建偏差较大。结论:体剂量验证系统EPIgray剂量重建与治疗计划系统计算剂量有较好的一致性,剂量重建精度能满足临床应用的需求。Objective:To assess the accuracy of dose reconstruction of the in-vivo dose verification EPIgray system in intensity-modulated radiation therapy(IMRT)and volumetric-modulated arc therapy(VMAT)through acceptance testing,and to explore the preliminarily clinical application of that.Methods:A total of 37 patients with cancer at various parts were selected for clinical testing.Referring to the suggestions of the acceptance manual of manufacturer and the American Association of Physicists in Medicine(AAPM)TG-119 report,the square field,strip field and intensity-modulated plan were adopted to test the precision of dose reconstruction of EPIgray system on phantom.The recognition ability of the system for error was researched through changed the thickness of homogeneous phantom and the skin distance of exposure source.A total of 37 patients with cancer at different parts who underwent VMAT were selected to conduct clinical test,and then,the consistence between the dose reconstruction of EPIgray system and the counted dose of treatment plan system were further analyzed.Results:In the tests of square field,EPIgray dose reconstruction demonstrated excellent linearity and higher accuracy.On the phantoms with different thicknesses of fields with different sizes,the highest precision of dose reconstruction of central axis of field was(0.10±0.39)%.The all precisions of dose reconstruction were within 3.0%besides the built region of dose and field edges.In the tests of IMRT and VMAT plan,the deviation of dose reconstruction was<5.0%.With the increasing of the complexity of plan and the heterogeneity of phantom,there was a slight decrease in the reconstruction precision,but all deviations of dose reconstruction were within the range of allowable deviations.In clinical testing of 37 patients,the average reconstruction deviation of the prescription dose point was(-0.6±4.8)%,and the average deviation of sampling points within the range of target area was(-2.1±2.7)%.The reconstruction deviations outside of field and that with larg

关 键 词:调强放射治疗(IMRT) 电子射野影像系统 容积旋转调强治疗(VMAT) 在体剂量学 质量保证 

分 类 号:R841.2[医药卫生—航空、航天与航海医学]

 

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