Safeguarding transcriptional memory: a mitotic bookmarking role for chromatin remodelers  

作　　者：Godwin Sokpor Huu Phuc Nguyen Tran Tuoc 

机构地区：[1]Department of Human Genetics,Ruhr University of Bochum,Bochum,Germany [2]Lincoln Medical School,University of Lincoln,Lincoln,UK

出　　处：《Signal Transduction and Targeted Therapy》2023年第11期5132-5133,共2页信号转导与靶向治疗（英文）

摘　　要：A recent study published in Nature reveals an interaction between SWI/SNF subunits and mitotic chromatin,which is essential for establishing gene bookmarks and preserving cell identity.1 The findings deepen our understanding of how SWI/SNF complexes regulate transcriptional memory heritability for cell fate commitment(Fig.1),thus validating the indispensability of SWI/SNF complexes in development and association of their perturbance with tumorigenesis and neurodevelopment disorders.

关 键 词：establishing COMPLEXES PRESERVING 

分 类 号：P59[天文地球—地球化学]