Tuning the Corrosion Resistance,Antibacterial Activity,and Cytocompatibility by Constructing Grooves on the Surface of Ti6Al4V3Cu Alloy  

作　　者：Minghui Zhou Hui Sun Yanming Gan Cheng Ji Yan Chen Yanjin Lu Jinxin Lin Qiang Wang 

机构地区：[1]Key Laboratory of Optoelectronic Materials Chemistry and Physics,Fujian Institute of Research on the Structure of Matter,Chinese Academy of Sciences,Fuzhou 350002,China [2]College of Chemistry,Fuzhou University,Fuzhou 350108,China [3]Liaoning Provincial Key Laboratory of Oral Diseases,School and Hospital of Stomatology,China Medical University,Shenyang 110002,China [4]Fujian College,University of Chinese Academy of Sciences,Fuzhou350002,China [5]Fujian Science and Technology Innovation Laboratory for Optoelectronic Information of China,Fuzhou 350108,China [6]College of Chemistry and Materials Science,Fujian Normal University,Fuzhou 350007,China

出　　处：《Acta Metallurgica Sinica(English Letters)》2023年第12期1979-1998,共20页金属学报（英文版）

基　　金：the study and collection,analysis,and interpretation of data were supported by the National Natural Science Foundation of China(No.51801198);the Funds of Scientific and Technological Plan of Fujian Province(Nos.2020Y9064,2020Y0083 and 2020L3026);Fujian Science&Technology Innovation Laboratory for Optoelectronic Information of China(No.2021ZZ111).

摘　　要：Ti6Al4V3Cu alloy is a promising biomaterial for combating implant-related infection.However,the antibacterial property of Ti6Al4V3Cu is expected to be enhanced due to the low content of Cu element in titanium.To address this issue,the antibacterial property of Ti6Al4V3Cu was tailored by the grooves with different groove widths(30μm,60μm,and 90μm)that were constructed on the surface of the Ti6Al4V3Cu by selective laser melting.The effect of grooves on corrosion resistance,antibacterial property,and cytocompatibility was investigated.The electrochemical tests showed that the corrosion resistance decreased with increasing groove width.The antibacterial tests indicated that the groove with a width of 30μm and 90μm groups showed better antibacterial activity against S.aureus(>90%)compared with the groove with a width of 60μm.The in vitro study suggested that all samples with different grooves were found to exhibit good cytocompatibility with osteoblast cells.It is considered that creating grooves on Ti6Al4V3Cu by selective laser melting is a promising strategy to enhance the antibacterial activity without sacrificing cytocompatibility.

关 键 词：Ti6Al4V3Cu GROOVE Corrosion resistance Antibacterial BIOCOMPATIBILITY 

分 类 号：TG174.4[金属学及工艺—金属表面处理]