穴位埋线联合中药内服治疗气虚型慢传输便秘的临床疗效观察  

Exploration of clinical efficacy of catgut embedding at acupoints combined with oral administration of traditional Chinese medicine on slow transit constipation due to qi deficiency

作　　者：董万青 张欣宇 张书信[3] DONG Wan-qing;ZHANG Xin-yu;ZHANG Shu-xin(Bejing University of Chinese Medicine,Bejing 100029,China;Research Ward,Bejing Anorectal Hospital(Bejing Erlong Road Hospital),Beijing 100120;Anorectal Department,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700)

机构地区：[1]北京中医药大学,北京100029 [2]北京市肛肠医院(北京市二龙路医院)研究型病房,北京100120 [3]北京中医药大学东直门医院肛肠科,北京100700

出　　处：《北京中医药》2023年第10期1083-1087,共5页Beijing Journal of Traditional Chinese Medicine

基　　金：北京市西城区财政科技专项项目计划(XCSTS-SD2022-10)。

摘　　要：目的以三焦脏腑理论为指导,观察穴位埋线联合中药内服治疗气虚型慢传输型便秘(STC)的临床疗效。方法选择北京市肛肠医院(北京市二龙路医院)2022年6月—9月收治的气虚型STC患者63例,采用随机数字表法分为2组。对照组给予枸橼酸莫沙必利片口服,5 mg/次,3次/d;聚乙二醇4000散口服,10 g/次,2次/d。观察组给予中药内服联合穴位埋线治疗。2组均治疗8周,比较2组临床疗效,治疗前、治疗8周的慢性便秘严重度评分量表(CSS)评分、结肠传输实验、血清一氧化氮(NO)、乙酰胆碱(Ach)、P物质(SP)、胃动素(MTL)及胃泌素(GAS);比较2组治疗前后生活质量自评量表(PAC-QOL)评分。结果观察组总有效率90.62%,高于对照组的64.52%(P<0.05)。治疗8周后,2组排便频率、排便费力、每次如厕时间、排便不成功次数及排便不尽感评分均较治疗前降低(P<0.05),且观察组各项评分低于对照组(P<0.05);2组标记物排出量均较治疗前增多(P<0.05),且观察组标记物排出量多于对照组(P<0.05);2组血清NO水平较治疗前降低,血清Ach、GAS、SP、MTL水平较治疗前升高(P<0.05),且观察组血清NO水平低于对照组,血清Ach、GAS、SP、MTL水平高于对照组(P<0.05)。治疗后,2组生活质量评分均较治疗前升高(P<0.05),且观察组生活质量评分高于对照组(P<0.05)。结论三焦脏腑理论指导下的穴位埋线联合中药内服可显著缓解气虚型STC患者便秘症状,提高临床疗效及患者生活质量。Objective To explore the clinical efficacy of acupoint catgut embedding combined with oral administration of traditional Chinese medicine in the treatment of slow transit constipation of qi deficiency type under the guidance of theory of Three Jiao Viscera.Methods A total of 63 outpatients admitted to the Beijing Anorectal Hospital(Beijing Erlong Road Hospital)from June 2022 to September 2022 were collected and randomly divided into a control group and an observation group using random number table method.The observation group was treated with acupoint catgut embedding combined with oral administration of traditional Chinese medicine,while the control group was treated with polyethylene glycol 4000 powder with 10 g/time and 2 times/d combined with mosapride citrate with 5 mg/time and 3 Times/d.Both groups were treated for 8 weeks.Comparative analysis was conducted on chronic constipation severity rating scale(CSS),colonic transit test results,serum NO,Ach,gastrointestinal hormone expression levels SP,MTL and GAS of patients before and after 8 weeks of treatment.The overall effective rate and quality of life(PAC-QOL self-assessment scale)scores of patients with constipation were compared after treatment.Results The total effective rate of the observation group was 90.62%,which was higher than that of the control group 64.52%(P<0.05).After 8 weeks of treatment,the frequency of defecation,defecation effort,time to go to the toilet every time,times of unsuccessful defecation and scores of incomplete defecation in the two groups were all lower than those before treatment(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05),and the amount of markers in the observation group was higher than that in the control group(P<0.05),and the serum levels of Ach,GAS,SP and MTL in the observation group were lower than those in the control group,while the serum levels of Ach,GAS,SP and MTL in the observation group were higher than those in the control group(P<0.05).The quality of life sc

关 键 词：三焦脏腑理论 穴位埋线 中药内服 气虚型 慢传输型便秘 

分 类 号：R256.35[医药卫生—中医内科学]