微针导入域发生发液治疗女性型脱发疗效观察  

Observation on the Therapeutic Effect of Microneedling Yufa Solution on Female Pattern Hair Loss

作　　者：马艳华[1] 魏爱华[1] 刘喜平[1] 尼建义 MA Yanhua;WEI Aihua;LIU Xiping;NI Jianyi(Department of Dermatology,Beijing Tongren Hospital Affiliated to Capital Medical University,Beijing 100000,China)

机构地区：[1]首都医科大学附属北京同仁医院皮肤科,北京100000

出　　处：《中国美容医学》2023年第12期107-111,共5页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探究微针导入域发生发液对女性型脱发(Female pattern hair loss,FPHL)患者治疗效果的影响。方法:选择2021年3月-2022年3月笔者医院收治的女性型脱发患者86例,随机分为对照组(n=43)和观察组(n=43)。对照组给予外涂5%米诺地尔搽剂,观察组给予微针导入域发生发液。比较两组临床疗效、新生发和脱发评分、皮肤镜征象、不良反应及生活质量[皮肤病生活质量指数(Dermatology life quality index,DLQI)]和不良情绪[汉密尔顿抑郁量表-17项(Hamilton depression scale,HAMD)]。结果:治疗后,观察组总有效率高于对照组(P<0.05),两组新生发和脱发评分均明显降低,且观察组低于对照组(P<0.05),两组皮肤镜征象发生率均降低,毛囊平均毛干数量均增多,且观察组改善优于对照组(P<0.05)。观察组不良反应总发生率略低于对照组(P>0.05),治疗后,两组DLQI评分均明显升高,HAMD评分均明显降低,且观察组DLQI评分较对照组高,HAMD评分较对照组低(P<0.05)。结论:采用微针导入域发生发液对治疗女性型脱发具有较好的临床疗效,可促进新发生长、抑制脱发,改善皮肤镜下征象,还可提高患者生活质量、缓解不良情绪。Objective To explore the effect of microneedling Yufa solution on female pattern hair loss(FPHL).Methods 86 female patients with alopecia admitted to the author's hospital from March 2021 to March 2022 were randomly divided into control group(n=43)and observation group(n=43).The control group was treated with 5%minoxidil liniment,and the observation group was treated with microneedling Yufa solution.The two groups were compared in terms of clinical efficacy,new hair and alopecia scores,dermoscopic signs,adverse reactions and quality of life[Dermatology Life Quality Index(DLQI)]and adverse emotions[Hamilton Depression Scale(HAMD)].Results After treatment,the total effective rate of the observation group was higher than that of the control group(P<0.05),the scores of new hair and alopecia of the two groups were significantly reduced,and the observation group was lower than that of the control group(P<0.05),the incidence of dermatological signs of the two groups was reduced,the average hair shaft number of hair follicles was increased,and the improvement of the observation group was better than that of the control group(P<0.05).The total incidence of adverse reactions in the observation group was slightly lower than that in the control group(P>0.05).After treatment,DLQI score was significantly increased and HAMD score was significantly decreased in both groups,and DLQI score was higher and HAMD score was lower in the observation group than that in the control group(P<0.05).Conclusion Microneedling Yufa solution has a good clinical effect on the treatment of female type alopecia.It can promote the growth of new hair,inhibit alopecia,improve of dermoscopic signs and has good safety.It can also improve the quality of life of patients and relieve adverse emotions.

关 键 词：微针 女性型脱发 皮肤镜 临床效果 安全性 域发生发液 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]