畜禽粪肥源抗生素抗性基因的生态风险评估  

Ecological Risk Assessment of Antibiotic Resistance Genes from Livestock Waste

作　　者：赵敏杏 温馨 陈涛 王军[1] 吴银宝[1,2,3] ZHAO Minxing;WEN Xin;CHEN Tao;WANG Jun;WU Yinbao(College of Animal Science and Technology,South China Agricultural University,Guangzhou,Guangdong 510642,China;Guangdong Laboratory for Lingnan Modern Agriculture and Technology,Guangzhou,Guangdong 510642,China;Maoming Branch,Guangdong Laboratory for Lingnan Modern Agriculture and Technology,Maoming,Guangdong 525000,China)

机构地区：[1]华南农业大学动物科学学院,广东广州510642 [2]岭南现代农业科学与技术广东省实验室,广东广州510642 [3]岭南现代农业科学与技术广东省实验室茂名分中心,广东茂名525000

出　　处：《家畜生态学报》2023年第12期90-96,共7页Journal of Domestic Animal Ecology

基　　金：岭南现代农业实验室科研项目(NZ2021027);茂名实验室科研启动项目(2021TDQD002);广东省现代农业产业技术体系生猪创新团队项目(2023KJ126)。

摘　　要：抗生素抗性基因(Antibiotic Resistance Genes,ARGs)作为一种新型环境污染物,对全球公共卫生安全构成重大威胁。畜禽粪污是ARGs的重要储存库,畜禽粪肥源ARGs的生态风险需要重点评估。本文在介绍污染物生态风险评估框架的基础上,明确ARGs的生态风险评估框架主要包括暴露评估、危害评估和风险表征这三个阶段。其次,说明了用于ARGs生态风险评估的数据库及评估方法,指出ARGs在种养结合过程的暴露路径、ARGs水平基因转移等是畜禽粪肥源ARGs生态风险评估的关键点。最后,提出适用于种养结合模式下ARGs在“畜禽-粪肥-土壤-植物-人类”链条中的生态风险评估框架。本文可为畜禽粪肥源ARGs的环境生态风险评估提供参考。Antibiotic resistance genes(ARGs),as an emerging environmental pollutant,pose a major threat on global public health safety.Livestock waste is an important reservoir of ARGs,so the ecological risk of ARGs in livestock waste needs to be assessed.Based on the introduction of the framework of ecological risk assessment on contaminants,the review firstly clarifies the three stages of ecological risk assessment framework of ARGs:exposure assessment,hazard assessment and risk characterization.Then,the review explains the database and assessment methods used for ARGs ecological risk assessment and points out that the key points of ARGs ecological risk assessment are ARGs exposure pathways,horizontal ARGs transfer during planting and breeding.Finally,the framework of ecological risk assessment for ARGs in the“livestock-waste-soil-plant-human”chain is proposed.The paper provides reference for the environmental and ecological risk assessment of ARGs from livestock waste sources.

关 键 词：畜禽粪肥 抗生素抗性基因 生态风险评估 水平基因转移 

分 类 号：S811.5[农业科学—畜牧学] X713[农业科学—畜牧兽医]