BMI正常的2型糖尿病患者内脏脂肪面积与心脑血管并发症的相关性分析  

Correlation between Visceral Fat Area and Cardiovascular and Cerebrovascular Complications in Type 2 Diabetes Patients with Normal BMI

作　　者：陈芬 杜爱敏 CHEN Fen;DU Aimin(Shangluo Central Hospital,Shangluo Shaanxi 726000)

机构地区：[1]商洛市中心医院,陕西商洛726000 [2]西安高新医院,陕西西安710075

出　　处：《医学临床研究》2023年第11期1690-1692,1696,共4页Journal of Clinical Research

摘　　要：【目的】探讨体重指数(BMI)正常的2型糖尿病(T2DM)患者内脏脂肪面积(VFA)与心脑血管并发症的相关性。【方法】回顾性分析2019年2月至2023年1月本院收治的110例BMI正常的T2DM患者的临床资料,根据有无心脑血管并发症将其分为对照组(无心脑血管并发症,n=39)与观察组(有心脑血管并发症,n=71)。比较两组患者VFA,采用Logistic多因素回归分析模型分析BMI正常的T2DM患者发生心脑血管并发症的影响因素,绘制受试者工作特征(ROC)曲线,分析VFA对BMI正常的T2DM患者发生心脑血管并发症的预测价值。【结果】观察组VFA高于对照组,差异有统计学意义(P<0.001)。观察组年龄、糖尿病病程、舒张压、收缩压、甘油三酯、低密度脂蛋白胆固醇、糖化血红蛋白、平均血小板体积高于对照组(P<0.05),高密度脂蛋白胆固醇、直接胆红素、间接胆红素低于对照组(P<0.05)。Logistic多因素回归分析结果显示,VFA升高、糖尿病病程长、间接胆红素降低、平均血小板体积升高为BMI正常的T2DM患者发生心脑血管并发症的影响因素(P<0.05)。ROC曲线结果显示,VFA预测BMI正常的T2DM患者发生心脑血管并发症的AUC值(95%CI)为0.793(0.690~0.875)(P<0.05)。【结论】BMI正常的T2DM患者VFA预测患者心脑血管并发症发生风险的价值较高。【Objective】To investigate the correlation between visceral fat area(VFA)and cardiovascular and cerebrovascular complications in type 2 diabetes patients with normal body mass index(BMI).【Methods】Retrospective analysis was conducted on the clinical data of 110 patients with T2DM with normal BMI admitted to our hospital from February 2019 to January 2023.They were divided into a control group(without cardiovascular and cerebrovascular complications,n=39)and an observation group(with cardiovascular and cerebrovascular complications,n=71)according to the presence or absence of cardiovascular and cerebrovascular complications.The VFA of the two groups of patients was compared,and the logistic multiple regression analysis model was used to analyze the influencing factors of cardiovascular and cerebrovascular complications in T2DM patients with normal BMI.The receiver operating characteristic(ROC)curve was drawn to analyze the predictive value of VFA for cardiovascular and cerebrovascular complications in T2DM patients with normal BMI.【Results】The VFA level in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.001).Age,course of diabetes,diastolic pressure,systolic pressure,triglyceride,low-density lipoprotein cholesterol,glycosylated hemoglobin,and mean platelet volume in the observation group were higher than those in the control group(P<0.05),while high-density lipoprotein cholesterol,direct bilirubin,and indirect bilirubin were lower than those in the control group(P<0.05).Logistic regression analysis showed that the increase of VFA,the long course of diabetes,the decrease of indirect bilirubin,and the increase of mean platelet volume were the influencing factors of cardiovascular and cerebrovascular complications in T2DM patients with normal BMI(P<0.05).The ROC curve results showed that the AUC value(95%CI)of VFA in predicting the occurrence of cardiovascular and cerebrovascular complications in T2DM patients with normal BMI was 0.793(0.6

关 键 词：糖尿病 2型 脂肪类/代谢 人体质量指数 心血管疾病 

分 类 号：R587.1[医药卫生—内分泌]