一种新型膝关节生物力学测试方法的设计与验证  

Design and validation of a novel knee biomechanical test method

作　　者：王俊瑞 赵智平[3,4] 姜程腾 聂闯[5] 时全星 刘猛 顾建文 WANG Junrui;ZHAO Zhiping;JIANG Chengteng;NIE Chuang;SHI Quanxing;LIU Meng;GU Jianwen(Savaid Medical School,University of Chinese Academy of Sciences,Beijing 100000,P.R.China;Department of Orthopaedics,Chengdu Second People's Hospital,Chengdu 610000,P.R.China;School of Biological Science and Medical Engineering,Beihang University,Beijing 100000,P.R.China;Department of Opthalmology,First Hospital of Jilin University,Changchun 130021,P.R.China;PLA Strategic Support Force Characteristic Medical Center,Beijing 100000,P.R.China)

机构地区：[1]中国科学院大学存济医学院,北京100000 [2]成都市第二人民医院骨外科,成都610000 [3]北京航空航天大学生物与医学工程学院,北京100000 [4]吉林大学第一医院眼科,长春130021 [5]中国人民解放军战略支援部队特色医学中心,北京100000

出　　处：《生物医学工程学杂志》2023年第6期1185-1191,1199,共8页Journal of Biomedical Engineering

基　　金：四川省科技厅中央引导地方项目科技发展专项(2022ZYD0096)。

摘　　要：本研究设计一种新的结构动力学测试方法及装置,用于测试动态轴向载荷对膝关节软骨与半月板的生物力学影响。首先,使用不同力锤对空载状态下实验装置施加轴向动载荷,计算实验装置的最大加速度信噪比。然后,将实验标本分为无标本组(空载,无标本)、假标本组(加载聚丙烯标本)、牛膝关节标本组(加载牛膝关节标本),进行测试。测试结果表明,该实验装置及方法可提供稳定的轴向动载荷,且实验结果有较好的可重复性。最终结果证实,通过本研究设计的装置可以有效区分实验标本的动态特性。本研究提出的实验方法为深入研究轴向动载荷作用下膝关节结构响应的生物力学机制提供了新的途径。A novel structural dynamics test method and device were designed to test the biomechanical effects of dynamic axial loading on knee cartilage and meniscus.Firstly,the maximum acceleration signal-to-noise ratio of the experimental device was calculated by applying axial dynamic load to the experimental device under unloaded condition with different force hammers.Then the experimental samples were divided into non-specimen group(no specimen loaded),sham specimen group(loaded with polypropylene samples)and bovine knee joint specimen group(loaded with bovine knee joint samples)for testing.The test results show that the experimental device and method can provide stable axial dynamic load,and the experimental results have good repeatability.The final results confirm that the dynamic characteristics of experimental samples can be distinguished effectively by this device.The experimental method proposed in this study provides a new way to further study the biomechanical mechanism of knee joint structural response under axial dynamic load.

关 键 词：结构动力学 膝骨关节炎 半月板损伤 生物力学 软骨损伤 

分 类 号：R318.01[医药卫生—生物医学工程] R684[医药卫生—基础医学]