昼夜节律与健康:中医与现代医学的对话  

Circadian rhythm and health:dialogue between traditional Chinese medicine and modern medicine

作　　者：易玉娟 孙康[2] 唐红 皮蓬莱 张书毅 李佳[2] 孙铮[1] YI Yu-juan;SUN Kang;TANG Hong;PI Peng-lai;ZHANG Shu-yi;LI Jia;SUN Zheng(Institute(College)of Integrative Medicine,Dalian Medical University,Dalian 116044,China;the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China)

机构地区：[1]大连医科大学中西医结合研究院,辽宁大连116044 [2]大连医科大学附属第一医院,辽宁大连116011

出　　处：《中国中药杂志》2023年第21期5681-5689,共9页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金青年基金项目(81702485);辽宁省教育厅基本科研面上项目(LJKZ0845);大连市高层次人才创新支持计划项目(2018RQ56);湖北陈孝平科技发展基金会2022年度肿瘤防治研究项目(CXPJJH122002-075)。

摘　　要：昼夜节律指机体一日性的节律变化。由于现代人生活方式的不规律导致慢性疾病高发,提示昼夜节律紊乱与疾病发生发展密不可分。传统中医对节律性变化阐述早在《黄帝内经》中就有记载,为节律研究奠定了丰富的理论基础,现代医学研究则对其分子机制提供了更全面的阐述。文章综合当前中西医领域对昼夜节律的认识,强调节律调控与疾病治疗的重要关系,突出两大学科结合的特点,为探索时间医学领域提供新的思考方向。Circadian rhythm refers to the daily rhythmic variations in an organism.The irregular lifestyles of modern humans have led to a high incidence of chronic diseases,highlighting an inseparable relationship between disrupted circadian rhythm and disease development.TCM has long discussed rhythmic variations,with records dating back to the Yellow Emperor′s Inner Canon(Huang Di Nei Jing),which laid a rich theoretical foundation for the research on circadian rhythm.Modern medical research has provided a more comprehensive explanation of its molecular mechanisms.This article integrated the current understanding of circadian rhythm in both Chinese and western medicine,emphasizing the crucial relationship between rhythm regulation and disease treatment.By highlighting the interdisciplinary nature of the two fields,it offers new directions for exploring the field of chronomedicine.

关 键 词：昼夜节律 生物钟基因 择时治疗 肠道菌群 时间医学 

分 类 号：R2-03[医药卫生—中医学]