针刺治疗抑郁症腧穴配伍规律及刺灸法应用特点  

Acupoint Compatibility Law and Application Characteristics of Acupuncture Moxibustion Treatment of Depression Based on Complex Network Analysis

作　　者：徐舒亭 王帅 徐媛[3] 赵舒蒙 孙师静 郭卓 XU Shuting;WANG Shuai;XU Yuan;ZHAO Shumeng;SUN Shijing;GUO Zhuo(Hebei Medical University,Shijiazhuang 050030,China;Shijiazhuang Gaocheng Integrated Traditional and Western Medicine Hospital,Shijiazhuang 052160,China;Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Xi'an Fanyi University,Xi'an 710105,China;Shijiazhuang Second Hospital,Shijiazhuang 050057,China)

机构地区：[1]河北医科大学,河北石家庄050030 [2]石家庄市藁城中西医结合医院,河北石家庄052160 [3]天津中医药大学,天津301617 [4]西安翻译学院,陕西西安710105 [5]石家庄市第二医院,河北石家庄050057

出　　处：《中国中医药信息杂志》2024年第1期29-35,共7页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家自然科学基金(82004473);河北省中医药管理局科研计划(2023130);河北医科大学青年科技创新人才托举培育计划(TJZR202010)。

摘　　要：目的基于复杂网络技术分析针刺治疗抑郁症的腧穴配伍规律及刺灸法应用特点,为抑郁症针刺处方的制定提供依据和思路。方法检索中国知网(CNKI)、万方数据知识服务平台(万方数据)、维普资讯中文期刊服务平台(VIP)、中国生物医学文献数据库(CBM)、PubMed、Embase、Cochrane Library、Web of Science建库至2022年9月21日针刺为主治疗抑郁症的相关临床研究文献,根据纳入排除标准筛选文献,建立针刺抗抑郁临床文献数据库,使用Excel2010对腧穴进行频次分析,运用SPSS Modeler 18.0进行关联规则分析,采用Gephi0.9.5进行复杂网络分析。结果共纳入文献579篇,涉及腧穴172个,使用总频次为3222。腧穴归经以督脉、足太阳膀胱经、足厥阴肝经为主;特定穴多选用原穴、输穴、背俞穴、络穴、八脉交会穴、募穴、合穴。关联规则分析显示,相关性最高的腧穴组合为“印堂-百会”。通过复杂网络k-core层次分析和社团分析得到2个核心腧穴群。针刺角度、深度、方向以安全性和经脉循行方向为依据;补泻手法以辨证分型为依据;组方时遵循辨证选穴和对症选穴。结论针刺治疗抑郁症以循经选穴和特定穴为主,核心腧穴以治神及调节脏腑经气和功能为主,临证注重辨证选穴和对症选穴,同时注重刺灸法效应特异性。Objective To analyze the acupoint compatibility law and the application characteristics of acupuncture moxibustion treatment for depression based on complex network technology;To provide a basis and ideas for formulating prescriptions of acupuncture antidepressant therapy.Methods Related clinical literature about acupuncture for the treatment of depression was retrieved from CNKI,Wanfang Data,VIP,CBM,PubMed,Embase,Cochrane Library,and Web of Science from the establishment of the databases to 21st,Sep.2022.According to the inclusion and exclusion criteria,the literature was screened,and the clinical literature database of acupuncture in antidepression was established.Excel 2010 was used for frequency analysis of acupoints.SPSS Modeler 18.0 was used for association rule analysis,and Gephi 0.9.5 was used for complex network analysis.Results Totally 579 articles were included,involving 172 acupoints,with a total frequency of 3222.The results of descriptive analysis showed that the main meridians of acupoints were Governor Vessel,bladder meridian and liver meridian,and the specific acupoints such as Yuan-primary point,Shu-stream point,Back-shu point,Luo-connecting point,Eight confluence points,Front-mu point,He-sea point were frequently used.Association rules analysis showed that the combination of the highest correlation acupoints were“Yintang(GV29)-Baihui(GV20)”.Through the complex network k-core analytic hierarchy process and community analysis,two core acupoint groups were finally obtained.The acupuncture angle,depth and direction were based on safety and meridian circulation direction,the tonifying and reducing method was based on syndrome differentiation,and the prescription was based on syndrome differentiation and symptomatic selection.Conclusion Acupuncture for depression has the following characteristics:the principle of acupoint selection is based on meridian selection and specific acupoints,the selection of core acupoints focuses on the treatment of spirit and the regulation of viscera,channels and fun

关 键 词：针刺 抑郁症 复杂网络分析 针刺处方 配伍规律 刺灸法 

分 类 号：R245[医药卫生—针灸推拿学] R2-05[医药卫生—中医临床基础]