AHP-熵权法结合Box-Behnken设计-响应面法优选党参精准煮散工艺  

Optimal Precision Decocting Process of Codonopsis Radix through Combination of AHP-Entropy Weight Method and Box-Behnken Design-Response Surface Method

作　　者：周晶晶 周洁 窦霞 靳子明 ZHOU Jingjing;ZHOU Jie;DOU Xia;JIN Ziming(Gansu University of Chinese Medicine,Lanzhou 730030,China;Affiliated Hospital of Gansu University of Chinese Medicine,Lanzhou 730030,China;Yang Xicang National Famous and Old Chinese Medicine Expert Studio,Lanzhou 730030,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730030 [2]甘肃中医药大学附属医院,甘肃兰州730030 [3]杨锡仓全国名老中医药专家工作室,甘肃兰州730030

出　　处：《中国中医药信息杂志》2024年第1期135-141,共7页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：甘肃省中医药管理局中医药防治重大疾病科研课题(2018ZD04);甘肃省中医药科研课题(GZKP-2022-23);兰州市城关区科技计划项目(2021-2-9)。

摘　　要：目的优选党参煮散的最佳粒度及煎煮工艺。方法以加水量、浸泡时间及煎煮时间为考察因素,以总黄酮、总多糖、干膏率为考察指标,运用AHP-熵权法结合Box-Behnken设计-响应面法确定党参煮散饮片的最佳粒度及煎煮工艺参数。结果党参煮散饮片的最佳粒度为4.00~4.75 mm(4~5目),最优煎煮工艺为加水量13倍,浸泡时间15 min,煎煮时间10 min。结论本研究优选出的党参煮散粒度科学合理,切合实际生产;确定的煎煮工艺方便快捷,合理可行,可为煮散的工业化生产提供依据。Objective To optimize the granularity and decocting process of Codonopsis Radix decoction.Methods Adding water,soaking time and decoction time were set as examine factors,and flavonoids,total polysaccharides,and extract yield were set as the indexes,AHP-entropy weight method combined with the Box-Behnken design-response surface method were used to determine the best particle size and the technological parameters of Codonopsis Radix decoction.Results The optimum size of precise Codonopsis Radix decoction was 4.00–4.75 mm(4–5 mesh);the optimum decocting process was 13 times the amount of water added;the soaking time was 15 min;the decocting time was 10 min.Conclusion The granularity of Codonopsis Radix decocting powder optimized in this study is scientific and reasonable,which is suitable for practical production.The established decocting process is convenient,reasonable and feasible,and provides a theoretical basis for the industrial production of decocting powder.

关 键 词：党参 精准煮散 AHP-熵权法 Box-Behnken设计-响应面法 最佳粒度 煎煮工艺 

分 类 号：R283.5[医药卫生—中药学]