普济消毒饮古代文献考证与分析  

Textual Research and Analysis on Ancient Literature of Puji Xiaodu Decoction

作　　者：郑陆峰 李鸿涛[1] 陈广坤[1] ZHENG Lufeng;LI Hongtao;CHEN Guangkun(Institute of Information of Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China)

机构地区：[1]中国中医科学院中医药信息研究所,北京100700

出　　处：《中国中医药图书情报杂志》2024年第1期16-21,共6页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

基　　金：第五批全国中医临床优秀人才研修项目(2022年);中国中医科学院基本科研业务优秀青年科技人才(传承类)培养专项(ZZ13-YQ-130);中国中医科学院科技创新工程课题重大攻关项目(CI2021A00505、CI2021A05302)。

摘　　要：搜集有关普济消毒饮的中医古籍文献,采用文献计量学方法对普济消毒饮的历史源流、药物组成、组方原理、剂量炮制、主治病证、用法等进行统计分析。经筛选得到普济消毒饮相关古籍文献235条,涉及中医古籍139部。普济消毒饮源于《东垣试效方》,由黄芩、黄连、人参、陈皮、玄参、甘草、连翘、牛蒡子、板蓝根、马勃、僵蚕、升麻、柴胡、桔梗14味中药组成,主要功效为清热解毒、疏风散邪,主治为上焦热盛所致的大头瘟等疾病。在涉及药味炮制的76条文献中,以甘草最多,多为生(44/45);其次为僵蚕,多为炒(38/44);黄连、黄芩多为酒炒(28/40、24/37);用法上以煮散剂为主,自明末剂型逐渐转变为汤剂。通过数据挖掘整理、系统分析记载普济消毒饮的中医古籍文献,为古代名方的临床应用和现代制剂研发提供参考。To collect ancient Chinese medicine literature related to Puji Xiaodu Decoction,and use bibliometric methods to statistically analyze the historical origin,drug composition,composition principle,dosage preparation,main disease symptoms,usage and other aspects of Puji Xiaodu Decoction.A total of 235 pieces of valid data were screened out,involving 139 TCM ancient books.It was found that Puji Xiaodu Decoction originated from Dong Yuan Shi Xiao Fang,which is composed of 14 kinds of Chinese materia medica,such as Scutellariae Radix,Coptis Chinensis,Ginseng Radix et Rhizoma,Citri Reticulatae Pericrpium,Scrophulariae Radix,Glycyrrhiza Radix Et Rhizoma,Forsythiae Fructus,Arctii Fructus,Isatidis Radix,Lasiosphaera Calvatia,Bombyx Batryticatus,Cimicifugae Rhizoma,Bupleuri Radix and Platycodonis Radix.The main efficacy is to clear heat and detoxify,dissipate wind and disperse pathogenic factors,and mainly treat diseases such as large-headed plague caused by scorched fever.Among the 76 articles concocted with medicinal processing,Glycyrrhiza Radix et Rhizoma was the most,and most of them were for raw use(44/45);followed by Bombyx Batryticatus,mostly fried(38/44);Coptis Chinensis and Scutellariae Radix were mostly stir-fried with wine(28/40,24/37);the usage was mainly based on the use of boiling powder,and the dosage form has gradually changed to decoction since the end of the Ming Dynasty.Through data mining and collation,systematic analysis and recording of ancient TCM literature of Puji Xiaodu Decoction, it provided a reference for the clinical application of ancient famous formulas and the research and development of modern preparations.

关 键 词：普济消毒饮 东垣试效方 中医古籍 考证 

分 类 号：R289.5[医药卫生—方剂学]