中医药调控内质网应激防治糖尿病视网膜病变研究进展  

Research Progress in the Prevention and Treatment of Diabetic Retinopathy by Regulating Endoplasmic Reticulum Stress with TCM

作　　者：马仙康 杨丽霞[2] 崔阳阳 米登海 MA Xiankang;YANG Lixia;CUI Yangyang;MI Denghai(Gansu University of Chinese Medicine,Lanzhou 730000,China;Gansu Provincial Institute of Traditional Chinese Medicine,Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃省中医药研究院,甘肃兰州730050

出　　处：《中国中医药图书情报杂志》2024年第1期261-264,共4页Chinese Journal of Library and Information Science for Traditional Chinese Medicine

基　　金：甘肃省科技计划(20JR10RA432)。

摘　　要：糖尿病视网膜病变(DR)是糖尿病微血管病变,内质网应激与其发生发展密切相关。在DR状态下,内质网应激参与了炎症、线粒体损伤、氧化应激、细胞凋亡等过程。本文系统阐述了DR的病因及病理概况、内质网应激的启动机制、内质网应激在DR发生发展中的具体作用,以及中医药靶向内质网应激防治DR的研究进展,以期为从事中医药防治DR领域的科研人员提供思路。Diabetic retinopathy(DR)is a microvascular disease of diabetes,and endoplasmic reticulum stress(ERS)is closely related to its occurrence and development.In the state of DR,ERS is involved in inflammation,mitochondrial damage,oxidative stress,apoptosis and other processes.This article systematically expounded the etiology and pathology of DR,the starting mechanism of ERS,the specific role of ERS in the occurrence and development of DR,and the research progress of TCM targeting ERS in the prevention and treatment of DR,in order to provide ideas for researchers engaged in the field of TCM to prevent and treat DR.

关 键 词：糖尿病视网膜病变 内质网应激 氧化应激 中医药 

分 类 号：R276.74[医药卫生—中医五官科学]