中药薰药温度阈值调控对湿热下注型附睾炎患者精子质量影响的临床研究  

Clinical study on the effect of temperature threshold control of traditional Chinese medicine fumigation on sperm quality in epididymitis patients with damp-heat downward type

作　　者：杨梅[1] 何丽萍[1] 孙慧芳[1] 吴瑾[2] 黄亚胜[1] 张亚群[1] 于雪瑶 高峰[1] YANG Mei;HE Liping;SUN Huifang;WU Jin;HUANG Yasheng;ZHANG Yaqun;YU Xueyao;GAO Feng(Department of,Urology and Andrology,Hangzhou Traditional Chinese Medicine Hospital,Hangzhou 310007,Zhejiang,China;Reproductive Laboratory,Hangzhou Traditional Chinese Medicine Hospital,Hangzhou 310007,Zhejiang,China)

机构地区：[1]杭州市中医院泌尿男科,杭州310007 [2]杭州市中医院生殖实验室,杭州310007

出　　处：《中国性科学》2023年第12期144-147,共4页Chinese Journal of Human Sexuality

基　　金：浙江省中医药科技计划项目(2022ZB245)。

摘　　要：目的探究不同温度下温控中药熏药技术对湿热下注型附睾炎患者精子质量及临床疗效的影响。方法纳入2022年6月至2023年6月在杭州市中医院泌尿男科治疗的108例急性附睾炎患者作为研究对象,按照随机数字表法分为A组、B组及C组,每组各36例。三组患者均应用温控中药薰药技术治疗,其中A组设置中药熏药温度为31~33℃、B组为34~36℃、C组为37~39℃。比较三组患者治疗前后前向运动精子百分率、正常形态精子百分率、精子浓度、舒适度、中医证候积分、临床疗效及安全性。结果治疗后7、14 d,B组患者前向运动精子比例、正常形态精子百分率、精子浓度、舒适度、临床疗效均高于A组及C组,中医证候积分显著低于A组及C组(P<0.05);三组患者依从性及不良事件发生率均无显著差异(P>0.05)。结论应用不同温度下温控中药熏药技术有利于改善附睾炎患者精子质量,提高附睾区舒适度,缓解附睾炎症状,控温范围在34~36℃时的临床疗效最显著。Objective To explore the effect of temperature control and traditional Chinese medicine(TCM)fumigation on sperm quality and clinical efficacy of epididymitis patients with damp-heat downward type at different temperatures.Methods A total of 108 patients with acute epididymitis treated in Department of Urology and Andrology,Hangzhou Traditional Chinese Medicine Hospital from June 2022 to June 2023 were selected as study subjects and randomly divided into group A,group B and group C(36 patients in each group).All the patients in the three groups were treated with temperature-controlled TCM fumigation technology,in which the fumigation temperature of TCM was 31-33℃in group A,34-36℃in group B and 37-39℃in group C.The proportion of forward motile sperm,normal morphology rate,sperm concentration,comfort degree,TCM syndrome score,clinical efficacy and safety were compared among the three groups before and after treatment.Results After 7 and 14 days of treatment,the average proportion of forward motile sperm,normal morphology rate,sperm concentration,comfort degree and clinical efficacy of group B were higher than those of group A and group C,and the average TCM syndrome score was significantly lower than those of group A and group C(P<0.05).There were no significant differences in compliance and incidence of adverse events among the three groups.Conclusions The application of temperature controlled Chinese herbal fumigation at different temperatures is beneficial to improve the sperm quality of epididymitis patients,improve the comfort degree of epididymis area and alleviate epididymitis symptoms.The clinical effect is most significant when the temperature-controlled range is 34-36℃.

关 键 词：附睾炎 温度 精子质量 临床研究 

分 类 号：R277.5[医药卫生—中医学]