基于数据挖掘分析中药治疗肛门坠胀的用药规律  

Medication rule of traditional Chinese medicine in treatment of anal pendant expansion:A study based on data mining

作　　者：赵沅 曾超群 胡响当[1] ZHAO Yuan;ZENG Chaoqun;HU Xiangdang(The Second Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410005,Hunan,China)

机构地区：[1]湖南中医药大学第二附属医院,湖南长沙410005

出　　处：《湖南中医杂志》2023年第11期40-43,共4页Hunan Journal of Traditional Chinese Medicine

基　　金：湖南省中医药科研计划项目(D2023008);湖南省中医肛肠专科诊疗中心项目;湖南中医药大学校级科研项目(2021XJJJ054)。

摘　　要：目的:基于数据挖掘探讨中药治疗肛门坠胀的用药规律。方法:收集中国知网(CNKI)、维普中文科技期刊数据库(VIP)、万方数据(WANFANG DATA)中自建库至2023年5月31日有关中医药治疗肛门坠胀的文献,根据纳入及排除标准进行筛选,建立数据库,采用聚类分析、关联规则等方法进行数据挖掘,并对药物频次、类别、性味归经、聚类及关联规则进行分析。结果:最终纳入文献45篇,方剂49首,中药139味,累计用药频次501次,使用频次较高的中药为当归、升麻、柴胡、炙甘草、白术等,功效以补虚、清热、理气、活血化瘀、利水渗湿为主,药性多为温、寒、平,药味多为苦、甘、辛,归经以脾、肝、胃经为主;挖掘出18个关联规则,聚类分析可分为4类,涉及秦艽苍术汤、补中益气汤等。结论:中药治疗肛门坠胀以补益中气为核心,随症治以清热利湿、活血化瘀、利水渗湿之法。Objective:To investigate the medication rule of traditional Chinese medicine(TCM)in the treatment of anal pendant expansion based on data mining.Methods:CNKI,VIP,and Wanfang Data were searched for articles on TCM treatment of anal pendant expansion published up to May 31st,2023,which were screened based on inclusion and exclusion criteria to establish a database.The methods such as cluster analysis and association rule analysis were used for data mining,and the drugs were analyzed in terms of frequency,category,nature/taste/meridian entry,cluster analysis,and association rule analysis.Results:A total of 45 articles were included,involving 49 prescriptions and 139 TCM drugs,with a total frequency of 501 times.The TCM drugs with a relatively high frequency of use included Angelica sinensis,Rhizoma Cimicifugae,Bupleurum chinense,Radix Glycyrrhizae Preparata,and Atractylodes macrocephala Koidz.,and the functions mainly included deficiency-tonifying herbs,heat-clearing drugs,Qi-regulating drugs,blood-activating and stasis-resolving drugs,and diuresis-inducing and dampness-draining drugs.Most drugs were warm,cold or neutral in nature and had a bitter,sweet,and pungent taste,and they mainly entered the spleen,liver,and stomach meridians.A total of 18 association rules were obtained,and the drugs were clustered into 4 categories based on the cluster analysis,involving Gentiana macrophylla-Rhizoma Atractylodis decoction and Buzhong Yiqi decoction.Conclusion:Tonifying middle Qi is the core of TCM treatment of anal pendant expansion,and the methods such as heat-clearing and diuresis-inducing therapy,blood-activating and stasis-resolving therapy,and diuresis-inducing and dampness-draining therapy are used based on symptoms.

关 键 词：肛门坠胀 中医药 数据挖掘 用药规律 

分 类 号：R259.748[医药卫生—中西医结合]