电感耦合等离子体-质谱法测定工作场所空气中碘  

Determination of iodine in workplace air by inductively coupled plasma mass spectrometry

作　　者：朱莎 何漪[1,2] 常通 王勤[1,2] 高慧 李婷婷[1,2] 魏滨 刘月月[1,2] 王韬 ZHU Sha;HE Yi;CHANG Tong;WANG Qin;GAO Hui;LI Tingting;WEI Bin;LIU Yueyue;WANG Tao(Sanitary Inspection Department of Zibo Center for Disease Control and Prevention,Zibo,Shandong 255026,China;不详)

机构地区：[1]淄博市疾病预防控制中心卫生检验中心,山东淄博255026 [2]淄博市环境有机污染物与人群健康监测分析重点实验室,山东淄博255026

出　　处：《中国职业医学》2023年第4期447-450,共4页China Occupational Medicine

基　　金：山东省医药卫生科技发展计划项目(202112010542)。

摘　　要：目的建立溶剂解吸电感耦合等离子体-质谱(ICP-MS)法测定工作场所空气中碘的方法。方法以碱性活性炭管采集工作场所空气中的碘,分别以10.0 mL纯水或浓度为20 mmol/L的碳酸氢钠溶液解吸,以铼-185为内标定量,以ICP-MS仪分别在标准模式和动能歧视的碰撞(KED)模式下检测。结果标准模式下,碘在质量浓度为9.0~1100.0μg/L时线性关系良好,相关系数为0.9993,检出限为2.7μg/L。KED模式下,碘在质量浓度为24.3~800.0μg/L时线性关系良好,相关系数为0.9991,检出限为7.3μg/L。采用纯水解吸的平均解吸效率为99.1%~106.7%,批内相对标准偏差(RSD)为3.1%~8.0%,批间RSD为4.9%~9.3%;采用碳酸氢钠溶液解吸的平均解吸效率为96.5%~105.3%,批内RSD为4.9%~8.6%,批间RSD为2.5%~9.9%。平均解吸效率和批间RSD在解吸液和ICP-MS检测模式的主效应上以及两者的交互效应上均无统计学意义(P值均>0.05)。样品在室温下至少可保存7 d。结论所建立的方法灵敏度高,准确性好,样品前处理简单、快捷,适用于工作场所空气中碘的测定。Objective To establish a solvent desorption inductively coupled plasma-mass spectrometry(ICP-MS)method for determination of iodine in workplace air.Methods Iodine in workplace air was collected with alkaline activated carbon tube and desorbed with 10.0 mL pure water or 20 mmol/L sodium bicarbonate solution.Rhenium-185 was used as an internal standard for quantification.The sample was determined in standard mode and kinetic energy discrimination collision(KED)mode by ICP-MS.Results In standard mode,iodine showed a good linear range in the concentration of 9.0 to 1100.0μg/L,with a correlation coefficient of 0.9993 and a detection limit of 2.7μg/L.In KED mode,iodine showed a good linear range in the concentration of 24.3 to 800.0μg/L,with a correlation coefficient of 0.9991 and a detection limit of 7.3μg/L.The average desorption efficiency using pure water ranged from 99.1%to 106.7%,with within-run relative standard deviation(RSD)of 3.1%to 8.0%and between-run RSD of 4.9%to 9.3%.The average desorption efficiency using sodium bicarbonate solution ranged from 96.5%to 105.3%,with within-run RSD of 4.9%to 8.6%and between-run RSD of 2.5%to 9.9%.There were no statistical significant differences in the main effects of desorption solution,ICP-MS detection mode,their interaction on average desorption efficiency and within-run RSD(all P>0.05).Samples could be stored at room temperature for at least 7 days.Conclusion This method is highly sensitive,accurate,and suitable for the determination of iodine in workplace air.The sample pretreatment is simple and rapid.

关 键 词：碘 工作场所 空气 溶剂解吸 电感耦合等离子体-质谱 

分 类 号：R134.4[医药卫生—劳动卫生]