电感耦合等离子体-质谱法测定工作场所空气中铊及其可溶性化合物  

Determination of thallium and its soluble compounds in workplace air by inductively coupled plasma mass spectrometry

作　　者：杨展鸿 吴川[1] 董明[1] 罗晓婷[1] 王伟辉[1] 黄钧宜 戎伟丰[1] 吴邦华[1] YANG Zhanhong;WU Chuan;DONG Ming;LUO Xiaoting;WANG Weihui;HUANG Junyi;RONG Weifeng;WU Banghua(Institute of Chemical Surveillance,Guangdong Province Hospital for Occupational Disease Prevention and Treatment,Guangzhou,Guangdong 510300,China)

机构地区：[1]广东省职业病防治院毒化监测所,广东广州510300

出　　处：《中国职业医学》2023年第4期451-454,460,共5页China Occupational Medicine

基　　金：广东省医学科学技术研究基金(B2021033);广东省化学中毒与核辐射突发事件医学救援应急技术研究中心(2016A020224005)。

摘　　要：目的建立微孔滤膜采样、电感耦合等离子体-质谱(ICP-MS)法测定工作场所空气中铊及其可溶性化合物的方法。方法采用微孔滤膜采集工作场所空气中的铊及其可溶性化合物,以硝酸消解后,采用镥内标法定量,以ICP-MS仪检测。结果铊的质量浓度在0.00~600.00μg/L时线性关系良好,相关系数为1.000,检出限为0.08μg/L,定量下限为0.26μg/L;以采集75.00 L工作场所空气样品计算时,铊的最低检出浓度、最低定量浓度分别为1.0×10^(-5)和3.0×10^(-5)mg/m^(3);以采集480.00 L空气样品计算时,铊的最低检出浓度和最低定量浓度分别为2.0×10^(-6)和5.0×10^(-6)mg/m^(3);加标回收率为100.82%~103.44%,批内、批间相对标准偏差分别为1.50%~3.32%和1.32%~3.11%;样品在室温下至少可保存14 d。结论本方法适用于工作场所空气中铊及其可溶性化合物的检测。Objective To establish a method for the determination of thallium and its soluble compounds in workplace air using microporous filter membrane sampling and inductively coupled plasma mass spectrometry(ICP-MS).Methods Thallium and its soluble compounds in workplace air were collected using microporous filter membranes,digested with nitric acid,quantified using lutetium internal standard method,and detected by ICP-MS.Results The linear range of thallium was 0.00 to 600.00μg/L,with the correlation coefficient of 1.000.The detection limit was 0.08μg/L,and the lower limit of quantification was 0.26μg/L.The minimum detection concentration and minimum quantitation concentration of thallium of 75.00 L workplace air were 1.0×10^(-5)and 3.0×10^(-5)mg/m^(3),respectively.The minimum detection concentration and minimum quantitation concentration of thallium of 480.00 L workplace air was 2.0×10^(-6)and 5.0×10^(-6)mg/m^(3),respectively.The recovery rate of spiking was 100.82%-103.44%,and the relative standard deviation within-and between-batches was 1.50%-3.32%and 1.32%-3.11%,respectively.The sample could be stored at room temperature for at least 14 days.Conclusion This method can be used for the detection of thallium and its soluble compounds in workplace air.

关 键 词：铊 电感耦合等离子体-质谱 工作场所 空气 

分 类 号：R134.4[医药卫生—劳动卫生]