机构地区:[1]湖州师范学院护理学院,湖州313000 [2]湖州市中心医院采供中心,湖州313099 [3]徐州医科大学附属医院麻醉科,徐州221002
出 处:《国际麻醉学与复苏杂志》2023年第11期1164-1167,共4页International Journal of Anesthesiology and Resuscitation
摘 要:目的:探讨10°reverse-Trendelenburg体位联合多拉司琼预防甲状腺手术女性患者术后恶心呕吐(postoperative nausea and vomiting, PONV)的临床效果。方法:采用便利抽样法选择2021年1月-2021年2月于徐州医科大学附属医院进行甲状腺手术的女性患者150例,按照随机数字表法分为多拉司琼组(D组)和10°reverse-Trendelenburg体位联合多拉司琼组(T组),每组75例。D组患者仅使用多拉司琼预防PONV,T组患者采用10°reverse-Trendelenburg体位联合多拉司琼预防PONV。比较两组患者术后48 h内PONV的发生率,记录两组失血量、术中低血压发生率、VAS疼痛评分、头晕和头痛发生率、补救止吐药的使用情况、住院时间、恢复质量评分及外科医师满意度。结果:D组PONV发生率为34.7%(25/72),T组PONV发生率为12.5%(9/72),两组比较差异有统计学意义,T组与D组PONV发生率的相对危险度为0.36(95%CI 0.18~0.72, P=0.002)。T组患者失血量明显低于D组( P=0.001);两组患者术中低血压发生率、VAS疼痛评分及头晕和头痛发生率比较,差异无统计学意义( P>0.05);T组需要补救止吐的患者明显少于D组( P=0.002);两组患者住院时间差异无统计学意义( P>0.05);T组患者恢复质量评分明显高于D组( P<0.001);两组在外科医师满意度方面差异无统计学意义( P>0.05)。 结论:10°reverse-Trendelenburg体位联合多拉司琼比单独使用多拉司琼对甲状腺手术女性患者PONV的预防效果更佳。Objective To investigate the clinical effect of 10°reverse‐Trendelenburg position combined with dolasetron on preventing postoperative nausea and vomiting(PONV)in female patients undergoing thyroid surgery.Methods A total of 150 fe‐male patients who underwent thyroid surgery at the Affiliated Hospital of Xuzhou Medical University from January 2021 to February 2021 were selected using convenience sampling method.According to the random number table methods,they were divided into two groups(n=75):a control group(group D)and an observation group(group T).Patients in group D received dolasetron alone for prevent‐ing PONV,while those in group T received 10°reverse‐Trendelenburg position combined with dolasetron.Then,their incidences of PONV within 48 h after surgery were compared.The blood loss,incidence of intraoperative hypotension,Visual Analog Scale(VAS)scores,incidences of dizziness and headache,use of rescue antiemetics,length of hospitalization stay,scores of the quality of recovery,and surgeon satisfaction were recorded.Results The incidence of PONV was 34.7%(25/72)for group D and 12.5%(9/72)for group T,with statistical difference.The relative risk of PONV incidence between group T and group D was 0.36[(95%confidence interval(CI)0.18,0.72),P=0.002].Group T had significantly less blood loss than group D(P=0.001).No statistical difference was found in the incidence of intraoperative hypotension,VAS scores,and the incidences of dizziness and headache between the two groups(P>0.05).Patients in group T required less rescue antiemetics than group D(P=0.002).There was no statistical difference in the length of hospi‐talization stay between the two groups(P>0.05),and the scores of the quality of recovery was significantly higher in group T than those in group D(P<0.001).There was no statistical difference in surgeon satisfaction between the two groups(P>0.05).Conclusion The 10°reverse‐Trendelenburg position combined with dolasetron is more effective than dolasetron alone in preventing postoperative naus
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