银杏叶有效成分提取的放大研究  

Study on Amplification of Extraction of Effective Components from Ginkgo Biloba Leaves

作　　者：王博 王子涵 段博文 刘旭琦 冯俊 黄卫东[1] WANG Bo;WANG Zi-han;DUAN Bo-wen;LIU Xu-qi;FENG Jun;HUANG Wei-dong(Hubei Polytechnic University,Huangshi Hubei 435000;Dynamic Electronics(Huangshi)Co.,Ltd.,Hubei Huangshi 435000;Wuhan University of Science and Technology,Hubei Wuhan 430081,China)

机构地区：[1]湖北理工学院,湖北黄石435000 [2]定颖电子(黄石)有限公司,湖北黄石435000 [3]武汉科技大学,湖北武汉430081

出　　处：《广州化工》2023年第15期64-66,共3页GuangZhou Chemical Industry

基　　金：教育部产学合作协同育人项目(201902313008);湖北省教育厅项目(B2013060);湖北省重点实验室项目(201210)。

摘　　要：以银杏叶黄酮含量为指标,使用乙醇为提取剂,温度、时间、液固相比、粉碎度为提取因素,探索放大实验的响应面优化实验,确定最佳工艺条件。通过小试实验,确定最佳条件:温度75℃,时间70 min,液固比11∶1,粉碎度在120~100目。以温度、时间和液固比为响应面优化条件。中试优化响应面优化条件为:温度75℃,时间70 min,液固比11∶1,提取率可高达12.03%。The content of active components in ginkgo biloba leaves was determined.Extraction factors included temperature,time,liquid-solid ratio and grinding degree.On this basis,the response surface optimization experiment of amplification experiment was explored.Compared the differences and common points between pilot and small tests,the best process conditions were determined.Through the test in experiment,the optimum conditions were as follows:reaction temperature was 75℃,reaction time was 70 min,liquid-solid ratio was 11∶1,crushing degree in 120 mesh to 100 mesh.The response surface optimization conditions were as follows:reaction temperature was 75℃,reaction time was 70 min,liquid-solid ratio was 11∶1,extraction rate could be as high as 12.03%.

关 键 词：银杏叶 总黄酮 中试放大 响应面优化。 

分 类 号：R944.6[医药卫生—药剂学]