左心室辅助装置置入同期干预术前严重二尖瓣反流的现状及研究进展  

Concomitant intervention for significant preoperative mitral regurgitation during left ventricular assist device implantation:current state and perspectives

作　　者：王志华[1] 程兆云[1] 胡俊龙[1] 宋瑶珏 孙俊杰[1] 赵泽原 李浩琦 Wang Zhihua;Cheng Zhaoyun;Hu Junlong;Song Yaojue;Sun Junjie;Zhao Zeyuan;Li Haoqi(Department of Cardiac Surgery,Central China Fuwai Hospital of Zhengzhou University,Zhengzhou 451464,China)

机构地区：[1]郑州大学华中阜外医院心外科,郑州451464

出　　处：《中华胸心血管外科杂志》2023年第11期692-696,共5页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：河南省重点研发专项(221111310300);河南省医学科技公关计划项目(LHGJ20220111,SBGJ202101005)。

摘　　要：全球心力衰竭(heart failure,HF)的患病率日益增长,二尖瓣反流(mitral regurgitation,MR)是终末期HF患者的常见表现。目前,左心室辅助装置(left ventricular assist device,LVAD)置入同期手术干预术前严重MR的适应证仍有较多争议。本文在论述终末期HF患者功能性MR的病因、分型及病理生理学的基础上,针对影响此类患者预后的相关因素及LVAD置入是否同期手术干预术前严重MR的相关研究进展作简要综述,以期为临床实践提供进一步参考依据。The prevalence of heart failure(HF)is increasing worldwide,and mitral regurgitation(MR)is a common manifestation in patients with end-stage HF.Currently,the indications for concomitant surgical intervention of significant preoperative MR during left ventricular assist device(LVAD)implantation are still controversial.Based on discussing the etiology,classification,and pathophysiology of functional MR in patients with end-stage HF,this paper reviews the relevant factors affecting the prognosis of such patients and the progress of research related to whether to perform mitral valve surgery to intervene in significant MR during LVAD implantation,to provide a further reference for clinical practice.

关 键 词：左心室辅助装置 二尖瓣反流 病理生理学 MITRAL 临床实践 心力衰竭 常见表现 手术干预 

分 类 号：R541.6[医药卫生—心血管疾病]