心外膜脂肪组织与心脏外科术后新发心房颤动的研究进展  

Research progress of epicardial adipose tissue and postoperative atrial fibrillation after cardiac surgery

作　　者：杨子昂 凤玮[1] YANG Zi-ang;FENG Wei(Department of Cardiovascular Surgery,Fuwai Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College/National Center for Cardiovascular Diseases,Beijing 100037,China)

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外医院成人外科中心,北京市100037

出　　处：《中国心血管病研究》2023年第12期1138-1144,共7页Chinese Journal of Cardiovascular Research

基　　金：中国医学科学院阜外医院,国家心血管疾病临床医学研究中心自主课题(NCRC2020003)。

摘　　要：新发心房颤动(房颤)是心脏外科术后常见并发症之一,其可显著延长患者住院时长、增加医疗费用及发生不良事件的风险。术后新发房颤的发病机制尚不明确,可能与诸多因素有关。其中,心脏表面的脂肪组织在相关疾病发病过程中起到重要作用。然而,目前有关心外膜脂肪组织与心脏术后房颤的总结不多。本文拟从心外膜脂肪组织的解剖结构、病理生理学,以及其与术后房颤发生的潜在机制、相关预防治疗措施和未来展望等方面进行总结,为未来新的干预靶点提供参考。Postoperative atrial fibrillation(POAF)is one of the common complications after cardiac surgery,which can significantly prolong the time of hospital-stay and increase medical cost and the risk of adverse events.The mechanism of POAF is still unclear.It may be related with many factors,among which epicardial adipose tissue plays an important role in the developing process.At present,there are few summaries regarding epicardial adipose tissue and atrial fibrillation after cardiac surgery.This article aims to review studies on epicardial adipose tissue from the anatomy,pathophysiology,potential mechanisms related to the occurrence of POAF and relevant prevention measures,and the prospect on the future development to provide certain references for new intervention targets in the future.

关 键 词：心脏外科手术 心外膜脂肪组织 术后新发房颤 

分 类 号：R654.2[医药卫生—外科学]