动态心电监测对普萘洛尔治疗婴幼儿血管瘤后心律失常的诊断价值研究  

Study on the diagnostic value of dynamic electrocardiogram monitoring for arrhythmia after propranolol treatment in infants with hemangioma

作　　者：刘红芳 张燕 阳亮 LIU Hongfang;ZHANG Yan;YANG Liang(Department of ECG Room,Ganzhou Women and Children′s Health Care Hospital,Ganzhou,Jiangxi 341000,China)

机构地区：[1]赣州市妇幼保健院心电图室,江西赣州341000

出　　处：《现代医药卫生》2023年第24期4204-4206,4214,共4页Journal of Modern Medicine & Health

基　　金：赣州市科技计划项目(GZ2022ZSF317)。

摘　　要：目的探讨动态心电监测对普萘洛尔治疗婴幼儿血管瘤后心律失常的诊断价值。方法选取2022年1-9月赣州市妇幼保健院小儿外科收治的婴幼儿血管瘤患儿100例作为研究对象,均给予普萘洛尔治疗。按数字表法将患儿随机分为动态心电图组50例和常规心电图组50例,在服药前,服药2、5 d,4、12周时,分别采用24 h动态心电图或常规心电图进行心律失常监测。结果常规心电图组和动态心电图组总体上分别检测出经普萘洛尔治疗后发生心律失常的血管瘤患儿2例(4.0%)和12例(24.0%),两者比较,差异有统计学意义(P<0.05);在服药前,服药2、5 d和4周时,两组患儿的心律失常发生情况比较,差异无统计学意义(P>0.05);服药12周时,与常规心电图组相比,动态心电图组检出的心律失常患儿数量明显更多,差异有统计学意义(P<0.05)。结论随着采用普萘洛尔治疗婴幼儿血管瘤时长增加,患儿可出现心律失常不良反应,且动态心电图的检出率高于常规心电图,更具有临床诊断价值。Objective To explore the diagnostic value of dynamic electrocardiogram(ECG)monitoring in the treatment of arrhythmia after propranolol treatment in infants with hemangioma.Methods From January 2022 to September 2022,a total of 100 children with infantile hemangioma admitted to the Department of Pediatric Surgery of Ganzhou Women and Children′s Health Care Hospital were selected.All children were treated with propranolol.According to the method of random number table,the children were randomly divided into the dynamic ECG group(n=50)and the conventional ECG group(n=50).24 hours dynamic ECG or conventional ECG were used for arrhythmia monitoring before taking the medicine,2 days,5 days,4 weeks and 12 weeks after taking the medicine,respectively.Results During the study period,2 cases(4.0%)and 12 cases(24.0%)of hemangioma patients with arrhythmia after propranolol treatment were detected in the conventional ECG group and the dynamic ECG group,respectively,with statistically significant differences(P<0.05).There was no statistically significant difference between the two groups in the incidence of arrhythmia before the treatment,2 days,5 days and 4 weeks after medication(P>0.05).After 12 weeks of medication,compared with the conventional ECG group,the number of children with arrhythmia detected in the dynamic ECG group was significantly more,with statistically significant difference(P<0.05).Conclusion With the increase of the duration of propranolol treatment for infantile hemangioma,the adverse effects of arrhythmia may occur in children,and the detection rate of dynamic ECG is higher than that of conventional ECG,which have a more clinically diagnostic value.

关 键 词：婴幼儿血管瘤 动态心电监测 普萘洛尔 心律失常 

分 类 号：R445.9[医药卫生—影像医学与核医学]