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作 者:沈菲 张丹丽 姚建儿 陈天乐 钟勇 史晓林 陈天鹏 SHEN Fei;ZHANG Danli;YAO Jianer;CHEN Tianle;ZHONG Yong;SHI Xiaolin;CHEN Tianpeng(Department of Orthopedics,Zhuji Central Hospital,Shaoxing 311800,Zhejiang,China;The First Clinical College of Gannan Medical University,Ganzhou 341000,Zhejiang,China;Nanchang Hongdu Hospital of Traditional Chinese Medicine,Nanchang 330000,Jiangxi,China;The Second Clinical College of Zhejiang Chinese Medicine University,Hangzhou 310000,Zhejiang,China)
机构地区:[1]诸暨市中心医院骨科,浙江绍兴311800 [2]赣南医学院第一临床医学院,江西赣州341000 [3]南昌市洪都中医院,江西南昌330000 [4]浙江中医药大学第二临床医学院,浙江杭州310000
出 处:《中国现代医生》2023年第35期79-81,共3页China Modern Doctor
基 金:国家自然科学基金资助项目(81873129)。
摘 要:目的 探讨微信平台康复指导模式对骨质疏松性骨折患者再骨折的影响。方法 选取2018~2019年在浙江中医药大学附属第二医院骨科住院的100例骨质疏松性骨折患者,随机分为对照组和试验组,每组50例。两组出院用药均为阿仑膦酸钠、阿法骨化醇软胶囊、钙尔奇D片剂。对照组采用常规出院康复指导模式,试验组在此基础上实施微信平台康复指导模式,包括微信平台建设、详细干预模式。比较入院时及出院随访3年后两组骨密度变化、骨代谢水平[Ⅰ型前胶原氨基端原肽(procollagenⅠN-terminal propeptide,PINP)、β-异构C-端肽(beta-isomerized C-telopeptide, β-CTX)]及骨质疏松性骨折再发生率的差异。结果 试验组失访7例,对照组失访6例。试验组3年后骨密度明显高于对照组,对照组及试验组PINP、β-CTX都有显著下降,但试验组PINP下降幅度较缓(P<0.05),两组β-CTX比较,差异无统计学意义(P>0.05),再骨折发生率明显低于对照组,差异有统计学意义(P<0.05)。结论 运用微信平台康复指导模式能有效提高骨质疏松性骨折患者的骨密度,减缓骨形成指标(PINP)的下降,降低再骨折的发生率,但尚无证据表明微信平台康复指导模式对降低β-CTX有优势。Objective To explore the influence of WeChat platform rehabilitation guidance mode on refracture of osteoporotic fracture patients.Methods Totally 100 osteoporotic fracture patients admitted to the Department of Orthopedics of the hospital from 2018 to 2019 were selected and randomly divided into control group and experimental group with 50 patients in each group.The control group adopted the conventional discharge rehabilitation guidance mode,and the experimental group implemented WeChat platform rehabilitation guidance mode on this basis,including WeChat platform construction and detailed intervention mode.The changes of bone mineral density and the recurrence rate of osteoporotic fracture were compared between the two groups at admission and after 3 years of follow-up.Results There were 7 cases of lost follow-up in the experimental group,and there were 6 cases of lost follow-up in the control group.After 3 years,the bone mineral density of the experimental group was significantly higher than that of the control group,and the recurrence fracture rate was significantly lower than that of the control group(P<0.05).Conclusion The application of WeChat platform rehabilitation guidance mode can effectively improve bone density and reduce the incidence of refracture in osteoporotic fracture patients.
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