厚朴排气合剂联合经皮穴位电刺激对产后抑郁合并胃肠功能障碍患者胃肠功能及抑郁情绪的影响  

Clinical observation on the effect of magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation on postpartum depression complicated with gastrointestinal dysfunction

作　　者：王海锋[1] 孟怡 刘青[2] 景邵春[3] WANG Haifeng;MENG Yi;LIU Qing;JING Shaochun(Department of Obstetrics,Qinhuangdao Second Hospital,Qinhuangdao 066600,China)

机构地区：[1]秦皇岛市第二医院产科,河北秦皇岛066600 [2]秦皇岛市第二医院肾内科,河北秦皇岛066600 [3]秦皇岛市第二医院创伤关节科,河北秦皇岛066600

出　　处：《陕西中医》2024年第1期46-49,54,共5页Shaanxi Journal of Traditional Chinese Medicine

基　　金：河北省医学科学研究课题(20210582);河北省秦皇岛市科学技术研究与发展计划项目(201902A107)。

摘　　要：目的:探讨厚朴排气合剂联合经皮穴位电刺激对产后抑郁合并胃肠功能障碍的临床效果。方法:将120例产后抑郁合并胃肠功能障碍患者随机分为观察组(n=60)和对照组(n=60)。对照组给予经皮穴位电刺激治疗,观察组给予厚朴排气合剂联合经皮穴位电刺激治疗,疗程均为7 d。比较两组患者胃肠功能恢复情况、胃肠道障碍症状评分、胃泌素(GAS)、胃动素(MTI)、腹胀发生率、腹胀程度、汉密尔顿抑郁量表评分以及不良反应发生情况。结果:与对照组相比,观察组患者的肠鸣音恢复、首次肛门排气、首次排便、总住院时间明显更短(P<0.05)。治疗后,两组患者胃肠道障碍症状评分均明显下降,观察组低于对照组(P<0.05)。治疗后,两组患者GAS、MTI水平和治疗前相比均明显升高,且观察组高于对照组(P<0.05)。治疗后,观察组患者腹胀发生率为11.7%,低于对照组的30.0%(P<0.05)。治疗后,观察组患者腹胀程度明显低于对照组(P<0.05)。治疗后,两组患者抑郁状态评分均明显下降,观察组低于对照组(P<0.05)。两组不良反应发生率(6.7%与5.0%)比较差异无统计学意义(P>0.05)。结论:厚朴排气合剂联合经皮穴位电刺激可有效促进产后抑郁合并胃肠功能障碍患者胃肠功能恢复,缓解腹胀和抑郁情绪,而且不会明显增加不良反应发生率。Objective:To explore the clinical effect of Magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation on postpartum depression with gastrointestinal dysfunction.Methods:120 postpartum depression patients with gastrointestinal dysfunction were randomly divided into an observation group(n=60)and a control group(n=60).The control group was treated with percutaneous acupoint electrical stimulation,while the observation group was treated with Magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation for 7 days.The recovery of gastrointestinal function,gastrointestinal disorder symptom score,gastrin(GAS),motilin(MTI),incidence and degree of abdominal distension,Hamilton Depression Scale score,and incidence of adverse reactions were compared between two groups of patients.Results:Compared with the control group,the observation group had shorter time of recovery of bowel sounds,first anal discharge,first bowel movement,and total hospital stay(P<0.05).After treatment,the scores of gastrointestinal disorders in both groups of patients significantly decreased,and the observation group was lower than the control group(P<0.05).After treatment,the levels of GAS and MTI in both groups of patients significantly increased compared to before treatment,and the observation group was higher than the control group(P<0.05).The incidence of abdominal distension in the observation group was 11.7%,lower than the 30.0%in the control group(P<0.05).The degree of abdominal distension in the observation group was significantly lower than that in the control group(P<0.05).The depression scores of both groups of patients significantly decreased,and the depression scores of the observation group were lower than those of the control group(P<0.05).The incidence of adverse reactions in the observation group was 6.7%,and there was no statistically significant difference compared to the control group’s 5.0%(P>0.05).Conclusion:The combination of Magnolia exhaust mixture and percutaneous acupoint ele

关 键 词：产后抑郁 胃肠功能障碍 腹胀 厚朴排气合剂 经皮穴位电刺激 不良反应 

分 类 号：R714.6[医药卫生—妇产科学]