巧克力球囊辅助药物涂层球囊血管成形术治疗TASCⅡC/D型股腘动脉病变的疗效分析  

Efficacy of chocolate balloon assisted drug⁃coated balloon angioplasty for the treatment of TASCⅡtype C/D femoropopliteal artery lesions

作　　者：李攀峰 李晓健 牛浩 LI Panfeng;LI Xiaojian;NIU Hao(Department of Vascular Surgery,Fuwai Central China Cardiovascular Hospital,Heart Center of He′nan Provincial People′s Hospital,Zhengzhou 450018,China)

机构地区：[1]阜外华中心血管病医院,河南省人民医院心脏中心,血管外科,郑州450018

出　　处：《实用医学杂志》2023年第23期3111-3115,共5页The Journal of Practical Medicine

基　　金：河南省医学科技攻关计划项目(编号:LHGJ20200094,LHGJ20210131)。

摘　　要：目的评价巧克力球囊辅助药物涂层球囊(DCB)血管成形术治疗TASCⅡC/D型股腘动脉病变的疗效及安全性。方法回顾性分析2021年1月至2022年10月在阜外华中心血管病医院接受巧克力球囊+DCB或普通球囊+DCB治疗的58例TASCⅡC/D型股腘动脉病变患者的临床资料,分为观察组(巧克力球囊+DCB)27例和对照组(普通球囊+DCB)31例。比较两组术中夹层发生率及术后临床疗效。结果观察组和对照组的技术成功率分别为88.9%和80.6%,观察组术中血管夹层、限流性夹层的发生率和补救性支架植入率均明显低于对照组(P<0.05)。术后两组患者临床症状均较术前明显改善,观察组12个月累积一期通畅率明显高于对照组(P<0.05)。两组12个月累积免于临床驱动的靶病变血运重建率差异无统计学意义(P>0.05)。结论巧克力球囊辅助DCB血管成形术治疗TASCⅡC/D型股腘动脉病变安全有效,可有效降低术中夹层发生率及补救性支架植入率,近期疗效优于普通球囊+DCB的治疗。Objective To evaluate the efficacy and safety of chocolate balloon assisted drug-coated balloon(DCB)angioplasty for the treatment of TASCⅡtype C/D femoropopliteal artery lesions.Methods The clinical data of 58 patients with TASCⅡtype C/D femoropopliteal artery lesions treated with chocolate balloon+DCB or plain balloon+DCB at Fuwai Central China Cardiovascular Hospital from January 2021 to October 2022 were retro⁃spectively analyzed.A total of 27 cases were assigned to the observation group(chocolate balloon+DCB)and 31 cases tothe control group(plain balloon+DCB).The rate of dissection and the clinical outcomes between the two groups were compared.Results The technical success rates of the observation and control groups were 88.9%and 80.6%,respectively.The rates of dissection,flow-limiting dissection,and bailout stenting were significantly lower in the observation group than of the control group(all P<0.05).Postoperative clinical symptoms of patients in both groups improved significantly compared with the preoperative period.The 12-month cumulative primary patency rate of the observation group was significantly higher than that of the control group(P<0.05).There was no significant difference in the 12-month cumulative freedom from clinically driven-target lesion revascularization rate between the two groups(P>0.05).Conclusion Chocolate balloonassisted DCB angioplasty was safe and effective for TASCⅡtype C/D femoropopliteal artery lesions.It reduced the rates of dissection and bailout stenting,and had better near-term outcomes than plain balloon+DCB.

关 键 词：股腘动脉病变 动脉硬化闭塞症 巧克力球囊 药物涂层球囊 血管成形术 

分 类 号：R654.4[医药卫生—外科学]