基于中医传承辅助平台探究关丽君教授治疗儿童睡眠障碍用药规律  

To explore the medication rules of Professor Guan Lijun′s treatment for children′s sleep disorders based on the TCM inheritance assistance platform

作　　者：曲笛[1] 郝雅文 关丽君[1] 王爽[1] 徐伊晗 高姗[1] QU Di;HAO Yawen;GUAN Lijun;WANG Shuang;XU Yihan;GAO Shan(Department of Rehabilitation Medicine,Shenyang Children′s Hospital,Shenyang 110032,China)

机构地区：[1]沈阳市儿童医院康复医学科,沈阳110032 [2]辽宁中医药大学,沈阳110032

出　　处：《中国中西医结合儿科学》2023年第6期518-523,共6页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：辽宁省中医大师传承工作室建设项目。

摘　　要：目的运用数据挖掘技术和统计学分析,研究总结关丽君教授治疗儿童睡眠障碍的用药特色及规律。方法通过回顾性研究的方法,收集整理关丽君教授2021年1月至2023年6月在沈阳市儿童医院治疗睡眠障碍的中医处方120首,采用中医传承平台(V2.5)软件对数据进行统计分析。结果使用频数>20次的共有22味中药,药性主要为温性、寒性、平性,药味主要为甘、苦、辛味,主入脾、心、肝、胃、肾经。关联规则分析得出25对药物配伍组合,11项关联规则,聚类分析结合临床经验得到4组可以用于新处方的聚类药物组合。结论关丽君教授治疗睡眠障碍是以滋肾水、补肝血、清热、宁心安神为法,以调理脾胃为核心,兼以宁心、疏肝、补肾的治疗原则,应用宁心安神、平肝潜阳、清热泻火、疏肝理气的治疗方法,为指导临床用药提供了新的见解。Objective To study and summarize the characteristics and rules of Professor Guan Lijun′s medication in the treatment of children′s sleep disorders by using data mining technology and statistical analysis.Methods Through retrospective study,120 TCM prescriptions for sleep disorders treated by Professor Guan Lijun in Shenyang Children′s Hospital from January 2021 to June 2023 were collected and analyzed statistically by TCM inheritance platform(V2.5)software.Results A total of 22 traditional Chinese medicines were used more than 20 times.Their properties were mainly warm,cold and calm,and their tastes were mainly sweet,bitter and spicy,mainly functioning through the spleen,heart,liver,stomach and kidney channels.By association rule analysis 25 pairs of drug compatibility combinations and 11 association rules were obtained;by cluster analysis combined with clinical experience 4 groups of cluster drug combinations were obtained,which could be used for new prescriptions.Conclusion Professor Guan Lijun′s treatment for sleep disorders is based on nourishing kidney water,replenishing liver blood,clearing heat,calming heart and calming the mind,centering on regulating spleen and stomach,and practicing the therapeutic principles of calming the heart,soothing the liver and tonifying the kidney.The therapeutic methods of calming the heart and calming the mind,calming the liver and suppressing Yang,clearing heat and expelling fire,and soothing the liver and regulating Qi are used,which provides new insights for guiding clinical medication.

关 键 词：睡眠障碍 用药规律 数据挖掘 聚类分析 儿童 

分 类 号：R729[医药卫生—儿科]