杏苏散加减治疗儿童反复呼吸道感染急性期咳嗽的临床疗效观察  

Clinical observation on acute cough of recurrent respiratory tract infections in children treated by Xingsu powder with modification

作　　者：熊加秀 赵晓敏 XIONG Jiaxiu;ZHAO Xiaomin(Second Affiliated Hospital of Jiangxi University of TCM,Nanchang 330000,China)

机构地区：[1]江西中医药大学第二附属医院儿科,南昌330000 [2]江西中医药大学第二附属医院内分泌科,南昌330000

出　　处：《中国中西医结合儿科学》2023年第6期523-526,共4页Chinese Pediatrics of Integrated Traditional and Western Medicine

基　　金：江西省中医药管理局科技计划项目(2021B146);江西省卫生健康委科技计划项目(202310724)。

摘　　要：目的观察杏苏散加减治疗儿童反复呼吸道感染急性期咳嗽风寒外束、痰饮内蕴证的临床疗效。方法选取2019年11月至2022年11月江西中医药大学第二附属医院儿科门诊诊断反复呼吸道感染急性期咳嗽风寒外束、痰饮内蕴证患儿108例,随机分成对照组和观察组各54例。对照组使用氨溴特罗口服溶液、吸入用布地奈德溶液等常规对症治疗,观察组在常规对症治疗基础上给予杏苏散加减治疗。经上述治疗6 d后,比较两组的临床疗效、临床症状积分、不良反应及继发慢性咳嗽情况。结果治疗后观察组临床总有效率为96.30%(52/54),高于对照组83.33%(45/54),临床症状积分较对照组显著下降,差异有统计学意义(P<0.05);治疗期间,两组不良反应发生率比较差异无统计学意义(P>0.05);跟踪随访4周,观察组慢性咳嗽继发率为11.11%(6/54),低于对照组25.93%(14/54),差异有统计学意义(P<0.05)。结论杏苏散加减治疗儿童反复呼吸道感染急性期咳嗽可提高临床疗效,改善症状,降低患儿慢性咳嗽继发率,值得临床推广。Objective To observe the clinical efficacy of Xingsu powder with modification in the treatment of acute cough of recurrent respiratory tract infections(RRTIs)with external evil inducing phlegm and fluid retention.Methods From November 2019 to November 2022,108 cases of acute cough of RRTIs with external evil inducing phlegm and fluid retention were treated in the pediatric outpatient department of the Second Affiliated Hospital of Jiangxi University of TCM,and they were selected and randomly divided into a control group and an observation group,with 54 cases in each group.The control group was given symptomatic treatment with ambroxol oral solution and inhalation of budesonide solution,and on this basis,the observation group was given Xingsu powder with modification.After 6 days of the above treatment,the clinical efficacy,clinical symptom score,adverse reaction and secondary chronic cough of the two groups were compared.Results After treatment,the total clinical efficiency rate of observation group was 96.30%(52/54),higher than that of control group(83.33%,45/54),and the clinical symptom score was significantly reduced compared with that of control group,the difference bring statistically significant(P<0.05);during the treatment,there was no statistical difference in the incidence of adverse reactions between the two groups(P>0.05);the 4-wee k follow-up showed that the rate of secondary chronic cough in observation group was 11.11%(6/54),lower than that in control group(25.93%,14/54)(P<0.05).Conclusion Xingsu powder with modification can improve the clinical effect,improve symptoms and reduce the rate of secondary chronic cough in children with acute cough of recurrent respiratory tract infections,which is worthy of clinical promotion.

关 键 词：反复呼吸道感染 慢性咳嗽 杏苏散 继发率 儿童 

分 类 号：R725.6[医药卫生—儿科]