香草酸和对羟基苯甲酸的电子光谱和解离常数的测定  

Determination of Electronic Spectra and Dissociation Constants of Vanillic Acid and p-Hydroxybenzoic Acid

作　　者：周利[1] 任佳 高肇林 桂玉娟 张晗[1] 夏雁青[1] 石铁生 Zhou Li;Ren Jia;Gao Zhaolin;Gui Yujuan;Zhang Han;Xia Yanqing*;Shi Tiesheng(College of Chemistry,Chemical Engineering and Materials Science,Zaozhuang University,Zaozhuang 277160,China)

机构地区：[1]枣庄学院化学化工与材料科学学院,山东枣庄277160

出　　处：《山东化工》2023年第22期173-176,共4页Shandong Chemical Industry

基　　金：枣庄学院化学生物学创新团队建设经费资助下完成

摘　　要：香草酸和对羟基苯甲酸都是存在于自然界中的天然抗氧化剂,具有抗菌、消炎和抗癌等生物活性。在25.0℃和1.0 mol/L离子强度下我们研究了它们在各种不同缓冲溶液中的电子光谱,并通过光度滴定的方法计算得到了二者在水溶液中的解离平衡常数pK_(a1)值和pK_(a2)值。在获得这些数据后就可以较为方便地对香草酸和对羟基苯甲酸的不同质子化形态随pH值的分布情况进行分析,这将对研究它们的抗氧化反应机理提供有力的支撑。Vanillic acid(VA)and p-hydroxybenzoic acid(HBA)are both natural antioxidants found in nature,which have good antibacterial,anti-inflammatory and anticancer properties.We have studied their UV-Vis spectra as a function of pH at 25.0℃and 1.0 mol/L ionic strength.Consequently,their acid dissociation constants pK a1 and pK_(a1) have been determined by a spectrophotometric titration method.With the acquired pK a1 and pK_(a1) values,the distributions of the protolytic species of VA and HBA with pH can be described explicitly,conferring a good foundation for studying their anti-oxidative mechanisms.

关 键 词：香草酸 对羟基苯甲酸 电子光谱 解离常数 

分 类 号：O657.3[理学—分析化学]