1例注射用奥美拉唑钠致过敏性休克病例的治疗分析  

Treatment Analysis of One Case of Anaphylactic Shock Induced by Omeprazole Sodium for Injection

作　　者：田亮玉 马红超 赵高亮 李文茜 TIAN Liang-yu;MA Hong-chao;ZHAO Gao-liang;LI Wen-qian(Department of Pharmacy,Zhengzhou Traditional Chinese Hospital of Orthopaedics,Zhengzhou 450016,China)

机构地区：[1]郑州中医骨伤病医院药剂科,郑州450016

出　　处：《中国合理用药探索》2023年第12期33-37,共5页Chinese Journal of Rational Drug Use

基　　金：河南省医学科技攻关计划项目(LHGJ20220898)。

摘　　要：目的:探讨注射用奥美拉唑钠在临床应用过程中的药品不良反应,以提高其临床使用的合理性和安全性。方法:临床药师通过回顾性分析1例药物过敏性休克患者的临床资料,探究注射用奥美拉唑钠可能引起患者药物过敏性休克的原因。结果:注射用奥美拉唑钠可引起患者出现药物过敏性休克,引起药物过敏性休克的主要原因为超适应症用药。结论:临床在使用注射用奥美拉唑钠时,需详细询问患者过敏史,严格按照《质子泵抑制剂临床应用指导原则》适应症给药,遵守给药原则。Objective:To probe into the adverse drug reactions in clinical application of omeprazole sodium for injection in order to improve the rationality and safety of its clinical use.Methods:Clinical pharmacists explored the possible causes of anaphylactic shock induced by omeprazole sodium for injection through retrospective analysis on the clinical data of one patient with drug anaphylactic shock.Results:Omeprazole sodium for injection can cause drug anaphylactic shock in patients,and the main cause of drug anaphylactic shock is off-label drug use.Conclusion:When using omeprazole sodium for injection,clinicians should ask patients about their allergic history in detail and prescribe according to indications specified in Guidelines for Clinical Use of Protein Pump Inhibitors and in compliance with administration guidelines.

关 键 词：注射用奥美拉唑钠 不良反应 过敏性休克 质子泵抑制剂 临床药师 

分 类 号：R969.3[医药卫生—药理学]