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作 者:张萌 杨戈[2] ZHANG Meng;YANG Ge(Changchun University of Chinese Medicine,Changchun 130117,China;The Affiliated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)
机构地区:[1]长春中医药大学,长春130117 [2]长春中医药大学附属医院,长春130021
出 处:《长春中医药大学学报》2023年第12期1400-1406,共7页Journal of Changchun University of Chinese Medicine
基 金:吉林省中医药科技项目(2023130)。
摘 要:生物标志物在心力衰竭(HF)的防治中起到了预测、早期诊断、指导治疗、预后评估、疗效评价等作用。与HF传统生物标志物(如BNP、hs-TnI等)相比,炎性生物标志物在HF中的功用主要体现在风险预测与预后评估方面。通过细致梳理近年来具有临床应用前景的HF炎性生物标志物的研究进展,论述以炎性生物标志物为靶点的中医药干预作用,以期为炎性生物标志物与传统生物标志物在HF防治中的联合应用提供新思考,并为完善中医药治疗HF的疗效评价提供新思路。Biomarkers play many positive roles in the prevention and treatment of heart failure(HF),such as prediction,early diagnosis,guidance for treatment,prognosis evaluation,and efficacy evaluation of this disease.Compared with traditional biomarkers of HF[such as brain natriuretic peptide(BNP),high sensitivity troponin I protein(hs-TnI),etc.],the role of inflammatory biomarkers in HF is mainly reflected in risk prediction and prognosis evaluation.By carefully combing the research progress of HF inflammatory biomarkers with clinical application prospects in recent years,this paper discusses the intervention role of traditional Chinese medicine targeting inflammatory biomarkers,in order to provide new thinking for the combined application of inflammatory biomarkers and traditional biomarkers in the prevention and treatment of HF,and to provide new ideas for improving the efficacy evaluation of traditional Chinese medicine in the treatment of HF.
分 类 号:R256[医药卫生—中医内科学]
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