李果实甲哌鎓与烯效唑残留量的差异及膳食风险评估  

Risk assessment for dietary residue intake and residual difference of mepiquat chloride and uniconazole in plum

作　　者：李萌[1] 周娟[1] 陈贺 马欢[1] 马婧玮[1] 许海康 李通[1] 安莉[1] 吴绪金[1] LI Meng;ZHOU Juan;CHEN He;MA Huan;MA Jingwei;XU Haikang;LI Tong;AN Li;WU Xujin(Institute of Quality and Safety for Agro-products,Henan Academy of Agricultural Sciences,Zhengzhou 450002)

机构地区：[1]河南省农业科学院农产品质量安全研究所,郑州450002

出　　处：《中国果树》2023年第12期35-41,46,共8页China Fruits

基　　金：中原科技创新领军人才(234200510012);河南省农业科学院科技创新团队(2023TD18);河南省农业科学院自主创新项目(2023ZC073)。

摘　　要：建立甲哌鎓和烯效唑在李果实中的残留检测方法,分析甲哌鎓和烯效唑残留量差异,评估2种农药残留长期和急性膳食摄入风险。样品前处理为QuEChERS方法,残留检测采用高效液相色谱-三重四极杆串联质谱法。李果实甲哌鎓和烯效唑在储藏183 d时,降解率分别为13%和14%,残留量在本试验条件下储藏较为稳定。李果实甲哌鎓和烯效唑在2个采样间隔期时残留量均小于0.01 mg/kg。甲哌鎓和烯效唑的普通人群国家估算每日摄入量(national estimated daily intake,NEDI)每千克体重分别是0.355 918、0.033 007 mg,分别占每日允许摄入量的2.90%和2.62%。李果实甲哌鎓和烯效唑的所有人群和儿童的国家估算短期摄入量(national estimated short term intake,NESTI)每千克体重均为0.000 095 4 mg;育龄妇女和普通人群及成年群体的国家估算短期摄入量每千克体重均为0.000 127 mg。李果实甲哌鎓的所有人群和儿童的国家估算短期摄入量占急性参考剂量的百分比(ARfD%)均为0.031 8%,育龄妇女和普通人群及成年群体的ARfD%均为0.042 3%;烯效唑的所有人群和儿童的ARfD%均为0.190 8%,育龄妇女和普通人群及成年群体的ARfD%均为0.254 0%。当基质、施药剂量和采收间隔期一致时,采收间隔期2 h时甲哌鎓与烯效唑的残留量有显著性差异,采收间隔期7 d和14 d时2种农药残留量差异不显著,原始沉积量(采样间隔2 h)与农药类型相关,最终残留量与农药消解半衰期和采样时间相关。Objective to study the detection methods of mepiquat chloride and uniconazole residues in plum.Analysis residue difference between mepiquat chloride and uniconazole under the same application measures,and risk assessment of chronic and acute dietary intake.Residue of mepiquat chloride and uniconazole was extracted by QuEChERS method,detected by LC-MS/MS.Residues of mepiquat chloride and uniconazole in plums after storage for 183 days,the degradation rates are 13%and 14%respectively,the residual quantity is relatively stable during storage under the conditions of this experiment.The residue levels of mepiquat chloride and uniconazole on plum in harvesting and 7 days after harvesting were all˂0.01 mg/kg.The national estimated daily intake of mepiquat chloride and uniconazole residue were 0.355918 mg and 0.033007 mg,respectively,and the ADI%was calculated according to formula and found to be 2.90%and 2.62%,respectively.The national estimated short term intake of mepiquat chloride and uniconazole in plums for all population groups and children(8 months to 16 years)were all 0.0000954 mg,for women of childbearing age(13~50 years)and general population(>1 year)and adult groups were all 0.000127 mg.The ARfD%of mepiquat chloride in plums for all population groups and children(8 months to 16 years)were all 0.0318%,for women of childbearing age(13~50 years)and general population(>1 year)and adult groups were all 0.0423%.The ARfD%of uniconazole in plums for all population groups and children(8 months to 16 years)were all 0.1908%,for women of childbearing age(13~50 years)and general population(>1 year)and adult groups were all 0.2540%.When the substrate,application dosage,and harvest interval are consistent,significant difference in mepiquat chloride and uniconazole residual amount 2 hour harvesting interval,there was no significant difference in mepiquat chloride and uniconazole residual amount 7 days and 14 days harvesting interval,the original deposition amounts is related to the type of pesticide,the final residual is re

关 键 词：甲哌鎓 烯效唑 残留量差异 膳食摄入风险评估 

分 类 号：S662.3[农业科学—果树学]