新生儿重症监护病房医院感染的影响因素分析  

Analysis of Influencing Factors of Nosocomial Infection in Neonatal Inten⁃sive Care Unit

作　　者：曾美红[1] 庄桂英[1] 周艳君 ZENG Meihong;ZHUANG Guiying;ZHOU Yanjun(Department of Neonatology,Guangzhou Huadu District Maternal and Child Health Hospital(Huzhong Hospital),Guangzhou,Guangdong Province,510800 China)

机构地区：[1]广州市花都区妇幼保健院(胡忠医院)新生儿科,广东广州510800

出　　处：《中外医疗》2023年第30期80-82,86,共4页China & Foreign Medical Treatment

摘　　要：目的分析新生儿重症监护病房的医院感染的影响因素。方法采用回顾式分析方法选取2016年1月—2020年12月广州市花都区妇幼保健院重症新生儿科收治的1632例单胎活产新生儿的临床资料,根据患儿是否感染分为感染组(n=62)和非感染组(n=1570),利用多因素Logistic回归探究新生儿重症监护病房医院感染风险因素。结果两组出生体重,无创正压通气,辅助持续通气≥96 h,气管插管,静脉插管,新生儿呼吸窘迫,以及新生儿喂养困难比较,差异有统计学意义(P<0.05)。多因素Logistic回归结果显示低出生体重、采用静脉插管和新生儿呼吸窘迫是院内感染的独立危险因素,差异有统计学意义(OR=8.252、3.833、2.232,P<0.05)。结论低出生体重是本院新生儿发生院内感染的最高危风险因素,同时静脉插管、新生儿呼吸窘迫也是引起院内感染的重要原因。因此,加强孕期营养,严格执行静脉插管无菌操作对降低发生院内感染具有重要意义。Objective To analyze the influencing factors of nosocomial infection in neonatal intensive care unit.Meth⁃ods A retrospective analysis method was used to select 1632 single live newborns admitted to the Intensive neonatol⁃ogy Department of Huadu District Maternal and Child Health Hospital,Guangzhou from January 2016 to December 2020.According to whether the children were infected,they were divided into infected group(n=62)and non-infected group(n=1570).Multivariate Logistic regression was used to explore the risk factors of nosocomial infection in the neonatal intensive care unit.Results Two groups of birth weight,noninvasive positive pressure ventilation,auxiliary continuous ventilation≥96 h,endotracheal intubation,intravenous cannula,neonatal respiratory distress,and compari⁃son and infant feeding difficulties,the difference was statistically significant(P<0.05).Multiariable Logistic regression results show that low birth weight and intravenous cannula and neonatal respiratory distress are independent risk fac⁃tors for nosocomial infection,the difference was statistically significant(OR=8.252,3.833,2.232,P<0.05).Conclu⁃sion Low birth weight is the highest risk factor for nosocomial infection of neonates in the hospital,and intravenous in⁃tubation and respiratory distress of neonates are also important causes of nosocomial infection.Therefore,it is of great significance to strengthen nutrition during pregnancy and strictly implement sterile operation of intravenous intubation to reduce nosocomial infection.

关 键 词：院内感染 新生儿 风险因素 重症监护病房 

分 类 号：R722[医药卫生—儿科]