莪术挥发油化学成分及其药理作用研究  

Study on the Chemical Constituents and Pharmacological Effects of theVolatile Oil from Zedoary Turmeric

作　　者：秦聪聪 杜沁圆 展照双 王加锋 QIN Congcong;DU Qinyuan;ZHAN Zhaoshuang;WANG Jiafeng(College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Ji'nan 250355,China)

机构地区：[1]山东中医药大学中医学院,济南250355

出　　处：《中国中医基础医学杂志》2024年第1期108-116,共9页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：齐鲁医派中医学术流派传承项目(齐鲁温病流派热病辨治中医药特色技术);齐鲁医派中医学术流派传承项目(齐鲁道地药材炮制存性中医药特色技术);山东省研究生教育质量提升计划(SDYKC21047);山东省研究生教育优质课程和专业学位研究生教学案例库(SDYAL20053)。

摘　　要：莪术挥发油为中药莪术发挥药用价值的主要活性部位,总结有关莪术挥发油化学成分的文献报道,发现目前从莪术挥发油中共鉴定出成分130余种,包括萜类(单萜、倍半萜)、酮(醛)类、醇(酚)类、烷(烯)烃类、酸(酯)类、醚类、芳香族等化合物,其中萜类为其主要化合物成分。莪术挥发油具有抗肿瘤、抗炎抑菌、抗病毒、抗血栓、保肝、保护神经、抗氧化等药理作用。目前,莪术挥发油所开发出的莪术油注射液、复方莪术油栓等广泛应用于临床。文章对莪术挥发油的提取工艺、化学成分及药理作用进行文献综述,以期为莪术挥发油在临床用药、制剂等方面提供参考。The volatile oil of Curcumae Rhizoma is the main active part of the medicinal value of Curcumae Rhizoma.The literature reports on the chemical constituents of the volatile oil of Zedoary turmerkc were summarized.It was found that more than 130 components were identified from the volatile oil of Zedoary turmerkc,including terpenoids(monoterpenoids,sesquiterpenoids),ketones(aldehydes),alcohols(phenols),alkanes,acids(esters),ethers,aromatics and other compounds,among which terpenoids were the main compounds.Curcuma volatile oil has anti-tumor,anti-inflammatory,anti-bacterial,anti-viral,anti-thrombosis,liver,nerve protection,anti-oxidation and other pharmacological effects.At present,curcuma oil injection and compound curcuma oil suppository developed by curcuma volatile oil are widely used in clinical practice.In this paper,the extraction process,chemical composition and pharmacological effects of volatile oil from Zedoary turmerkc were reviewed,in order to provide reference for clinical medication and preparation of volatile oil from Zedoary turmerkc.

关 键 词：莪术挥发油 化学成分 药理作用 萜类 

分 类 号：R285[医药卫生—中药学]