电化学方法检测还原型谷胱甘肽的研究进展  

Research Progress on Glutathione Detection Based on Electrochemical Methods

作　　者：魏世楠 赵灵芝[1] 张小清[1] 董旭阳 张硕 寇张文 党嘉怡 WEI Shi-nan;ZHAO Ling-zhi;ZHANG Xiao-qing;DONG Xu-yang;ZHANG Shuo;KOU Zhang-wen;DANG Jia-yi(Department of Pharmacy,Xi'an Medical College,Shaanxi Xi'an 710021,China)

机构地区：[1]西安医学院药学院,陕西西安710021

出　　处：《广州化工》2023年第16期19-22,共4页GuangZhou Chemical Industry

基　　金：2021年陕西省大学生创新项目(202111840014,121521014);西安医学院杰出人才青年计划配套项目(2021PT08);陕西省科技厅项目(2022JM-094)。

摘　　要：还原型谷胱甘肽(L-Glutathione,GSH)是具有生物活性重要的三肽化合物,其与氧化型谷胱甘肽(L-Glutathione oxidized,GSSG)两者相互转化维持着生物体内氧化还原平衡。GSH的含量与多种疾病密切相关。因此,发展一种准确、快速、灵敏、选择性高的检测方法十分必要。考虑到电化学检测GSH的优势,综述了近几十年来基于电化学技术发展的检测GSH的最新进展,并对其今后的发展趋势进行了展望。L-glutathione(GSH)is an important tripeptide with biological activity.GSH and L-glutathithione oxidized(GSSG)interconverted maintain redox equilibrium in organisms.Since the content of GSH is closely related to many diseases,it is necessary to develop the accurate,rapid,sensitive and highly selective detection methods.In view of the advantages of electrochemical detection of GSH,the latest development of GSH detection based on electrochemical technology in recent years was demonstrated,and its future development trend was prospected.

关 键 词：谷胱甘肽 电化学方法 纳米材料 电子介体 

分 类 号：O652[理学—分析化学]