超声在儿童传染性单核细胞增多症诊断和治疗中的应用  

Application of Ultrasound in the Diagnosis and Treatment of Infectious Mononucleosisin Children

作　　者：宋亚辉 马俊 丁旭萌[1] 韩玉培[1] Song Yahui;Ma Jun;Ding Xumeng;Han Yupei(Department of Ultrasound,Nanyang Second General Hospital,Nanyang,Henan 473008,China)

机构地区：[1]南阳市第二人民医院超声科,河南省南阳市473008

出　　处：《中国超声医学杂志》2023年第12期1379-1382,共4页Chinese Journal of Ultrasound in Medicine

基　　金：河南省医学科技攻关计划(联合共建)项目(No.LHGJ20191475)。

摘　　要：目的探讨超声检查对儿童传染性单核细胞增多症(IM)的诊断及治疗效果评估。方法收集确诊为IM患儿的临床资料,根据超声检查时间分为入院后24 h组(A组)、首诊症状好转后24 h组(B组)和出院前24 h组(C组)。结果42例符合诊断的患儿纳入研究,男22例,女20例,平均年龄(4.20±1.80)岁,临床表现以发热为最常见的首发症状(37例,88.1%),平均体温(38.6±0.8)℃,最高体温40.1℃。超声检查A组:肝脏增大19例(45.2%),脾脏增大20例(47.6%),颈部淋巴结增大36例(85.7%);B组:肝脏增大18例(42.9%),脾脏增大18例(42.9%),颈部淋巴结增大35例(83.3%);C组:肝脏增大10例(23.8%),脾脏增大11例(26.2%),颈部淋巴结增大28例(66.7%)。配对样本t检验示:(1)肝脏A组与C组、B组与C组差异存在统计学意义,t值分别为5.28、5.16,P<0.001,A组与B组差异无统计学意义,t值为0.12,P=0.907;(2)脾脏及颈部淋巴结A、B、C 3组两两配对比较组间均存在统计学意义(P<0.05)。结论超声检查有助于IM患儿的临床诊断和治疗效果的评估。Objective To explore the diagnostic value by ultrasonography and treatment of infectious mononucleosis(IM).Methods The clinical data of children diagnosed with IM were collected and divided into three groups according to the time of ultrasound examination:24 hours after admission(group A),24 hours after the first diagnosis of symptoms improved(group B)and 24 hours before discharge(group C).Results Forty-two children(22 males and 20 females)with a mean age of(4.20±1.80)years were included in the study,with fever as the most common initial symptom(37 cases,88.1%),mean body temperature(38.6±0.8)℃,and maximum body temperature 40.1 C.The ultrasonography presentations in group A included:19 cases with hepatomegaly(45.2%),Splenomegaly in 20 cases(47.6%),Cervical lymph nodes were enlarged in 36 cases(85.7%).In group B:18 patients demonstrated hepatomegaly(42.9%),Splenomegaly in 18 cases(42.9%),Cervical lymph nodes enlargement in 35 cases(83.3%).In group C:10 patients presented with hepatomegaly(23.8%),Splenomegaly in 11 cases(26.2%),Enlarged cervical lymph nodes were found in 28 cases(66.7%).The paired samplet test showed that①there were statistically significant differences between group A and group C,and between group B and group C as regards liver,with the t values being 5.28,and 5.16,respectively,P<0.001,and there was no statistically significant difference between group A and group B,with the t value being 0.12,P=0.907;②There were significant differences in splenic and cervical lymph nodes among the three groups(P<0.05).Conclusions Ultrasonography is helpful for the clinical diagnosis and therapeutic evaluation for children with IM.

关 键 词：传染性单核细胞增多症 儿童 EB病毒 超声诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学] R725.1[医药卫生—诊断学]