基于LED调光的频闪光刺激实验系统设计与实验验证  

Design and experimental validation of strobe stimulation experimental system based on LED dimming

作　　者：王梦辉 王小斐 任杰[3,4] 赵邑[3,4] 宋健[2,3] WANG Meng-Hui;WANG Xiao-fei;REN Jie;ZHAO Yi;SONG Jian(Tsinghua University Medical College,Beijing 100084,China;Department of Electronic Engineering,Tsinghua University,Beijing 100084,China;Photomedicine Laboratory,Institute of Precision Medicine of Tsinghua University,Beijing 100084,China;Beijing Tsinghua Changgung Hospital,Affiliated Hospital of Tsinghua University,Beijing 102218,China)

机构地区：[1]清华大学临床医学院,北京100084 [2]清华大学电子工程系,北京100084 [3]清华大学精准医学研究院光医学实验室,北京100084 [4]清华大学附属北京清华长庚医院,北京102218

出　　处：《医疗卫生装备》2023年第10期33-37,共5页Chinese Medical Equipment Journal

基　　金：清华大学精准医学科研计划项目(10001020131);清华-丰田联合研究基金。

摘　　要：目的:设计一种基于LED调光的频闪光刺激实验系统,并进行实验验证。方法:该系统包括LED调光系统和生理数据采集系统2个部分。其中LED调光系统主要由微处理器系统、LED驱动器和LED 3个部分组成,通过采用脉冲宽度调制(pulse-width modulation,PWM)技术调制驱动电流的占空比和频率来灵活控制LED的光强和闪烁频率;生理数据采集系统选用Biopac公司的16通道生理信号记录分析系统。应用该系统完成频闪光刺激实验,验证该系统的性能。结果:频闪光刺激实验表明,该系统可以精准控制LED的闪烁频率,并实时采集实验过程中受试者的皮肤电数据、心电图数据等生理数据,且频闪光刺激会使人的皮肤电数据和心电图数据发生改变。结论:该系统操作简单、使用方便,可用于研究频闪光刺激的光生物效应。Objective To design and experimentally validate a strobe stimulation experimental system based on LED dimming.Methods The experimental system consisted of a LED dimming system and a physiological data acquisition system,The LED dimming system was composed of a microprocessor system,a LED driver and a LED,which used pulse-width modulation(PWM)technology to modulate the duty cycle and frequency of the drive current to flexibly control the LED light intensity and flicker frequency;Biopac's 16-channel physiological signal recording and analysis system was used as the physiological data acquisition system.Strobe stimulation experiment was carried out to verify the performance of the system developed.Results The strobe stimulation experiment results showed the system developed could control the LED flicker frequency precisely and acquire the electrodermal data and ECG data of the subjects in real time,and the strobe stimulation resulted in changes of the electrodermal data and ECG data.Conclusion The system developed gains advantages in easy operation and can be used for exploring the photobiological ffect of the strobe stimulation.

关 键 词：LED调光 频闪光刺激 光生物效应 皮肤电数据 心电图数据 

分 类 号：R318[医药卫生—生物医学工程]