PET包装材料中聚酯低聚物的研究进展  

Research Progress of Polyester Oligomers in PET Packaging Materials

作　　者：冯佳宁 常世敏 吴刚[2] 仇凯[2] 夏伊宁 张敏 赵宇晖 FENG Jianing;CHANG Shimin;WU Gang;QIU Kai;XIA Yining;ZHANG Min;ZHAO Yuhui(College of Life Science and Food Engineering,Hebei University of Engineering,Hebei Handan 056038,China;China National Research Institute of Food&Fermentation Industries Co.,Ltd.,Beijing 100015,China;Institute of Food Science and Technology CAAS,Beijing 100193,China;Nanning Customs Testing Center for Dangerous Goods and Packaging,Jiangsu Changzhou 213000,China;ORG Technology Co.,Ltd.,Beijing 101407,China)

机构地区：[1]河北工程大学生命科学与食品工程学院,河北邯郸056038 [2]中国食品发酵工业研究院,北京100015 [3]中国农业科学院农产品加工研究所,北京100193 [4]南京海关危险货物与包装检测中心,江苏常州213000 [5]奥瑞金科技股份有限公司,北京101407

出　　处：《包装工程》2024年第1期118-127,共10页Packaging Engineering

基　　金：国家自然科学基金面上项目(32172315);国家自然科学基金国际(地区)合作与交流项目(32061160474)。

摘　　要：目的综述PET包装材料中聚酯低聚物的研究现状,包括筛查识别、迁移检测、风险评估及政策法规。方法PET包装材料中聚酯低聚物的筛查识别主要采用液相色谱-高分辨率质谱技术进行,结合靶向筛查和非靶向筛查手段。聚酯低聚物的迁移检测主要是测定不同条件聚酯低聚物从PET包装材料向食品模拟物的迁移。结果部分研究开展了真实食品中低聚物的含量测定,并采用合适的方法对食品样品进行前处理。聚酯低聚物的风险评估通常是将食品/食品模拟物中的迁移量和法规中的迁移限量进行比较。对法规中未列出的低聚物,通常采用毒理学关注阈值(TTC)方法结合Cramer决策树进行风险评估。由于实验数据的缺乏,针对PET内聚酯低聚物的法规还十分有限。结论随着PET包装材料的广泛使用,特别是新型PET包装材料的出现,有必要对PET中聚酯低聚物的潜在风险进行深入研究,以确保食品安全。应注重高分辨率质谱在聚酯低聚物筛查及迁移检测中发挥的作用,为后续风险评估提供重要数据支持。The work aims to review the current research progress of oligomers in PET packaging materials,including identification,migration detection,risk assessment,policies and regulations.Identification of oligomers in PET packaging materials was mainly conducted by liquid chromatography coupled to high resolution mass spectrometry(HRMS)with both targeted and non-targeted screening procedures.Migration detection of oligomers was carried out by measuring the amount of oligomers migrating from PET packaging materials to food simulants under different conditions.Detection of oligomers in real foods was also conducted,while appropriate sample pretreatment methods were applied.Risk assessment of oligomers was mainly performed by comparing the concentration of oligomers in food/food simulants with the corresponding migration limits either listed in policies and regulations or obtained via a threshold of toxicological concern(TTC)approach with implementation of Cramer classification scheme.By far,due to the lack of experimental data,policies and regulations on oligomers in PET are scarce.With the expanding application of PET in packaging,especially the commercialization of novel PET materials,it is quite necessary to fully investigate the potential risks of oligomers in PET to ensure food safety.It is believed that HRMS plays an important role in exploring oligomers in PET and their migration behaviors,which in turn could provide essential data for future risk assessment.

关 键 词：PET包装 聚酯低聚物 筛查识别 迁移检测 风险评估 政策法规 

分 类 号：TB487[一般工业技术—包装工程]