Catalyst光学体表监测在左侧乳腺癌ABC-DIBH放射治疗中的应用  

Application of Catalyst Optical Body Surface Monitoring in ABC-DIBH Radiotherapy for Left Side Breast Cancer

作　　者：刘剑锋 钟鹤立 张光伟 吴何苟 刘婷婷 高勇 李彬 LIU Jianfeng;ZHONG Heli;ZHANG Guangwei;WU Hegou;LIU Tingting;GAO Yong;LI Bin(Department of Radiation Oncology,Shenzhen People’s Hospital,Shenzhen Guangdong 518020,China)

机构地区：[1]深圳市人民医院肿瘤放疗科,广东深圳518020

出　　处：《中国医疗设备》2024年第1期61-66,共6页China Medical Devices

基　　金：国家自然科学基金面上项目(61871374)。

摘　　要：目的 探讨在应用主动呼吸控制(Active Breathing Control,ABC)技术的左侧乳腺癌深吸气屏气(Deep Inspiration Breath Hold,DIBH)放疗中,使用光学体表追踪技术监测屏气的有效性和体位的重复性效果,以保证患者在放疗中吸气方式一致和体位不变,提高放射治疗的精确性。方法 选取应用ABC技术放疗的23例左侧乳腺癌患者为研究对象,以Catalyst进行治疗中DIBH体位监测,以分次内锥形束计算机断层扫描(Cone Beam Computed Tomography,CBCT)为参考标准,分别记录二者误差数据,应用Pearson法和Bland-Altman法分别评估两组误差的相关性和两种系统的一致性。将光学体表监测值与CBCT配准误差值之间的差值定义为Catalyst体表监测精度。结果 Catalyst监测在左右(x轴)方向、头脚(y轴)方向和前后(z轴)方向误差分别为(0.08±1.04)、(1.44±2.15)、(0.45±1.69)mm,CBCT配准误差分别为(0.15±1.15)、(1.51±2.28)、(0.44±1.81)mm。x轴方向和z轴方向相关系数r值分别为0.60、0.77,呈强相关;y轴方向r值为0.82,呈极强相关。二者95%CI值在x、y与z轴方向分别为[-2.01,1.86]、[-2.69,2.57]、[-2.32,2.34] mm,Catalyst监测精度在x、y、z轴方向分别为(-0.08±0.99)、(-0.06±1.34)、(0.01±1.19)mm。结论 Catalyst可有效监测使用ABC进行治疗左侧乳腺癌患者的屏气状态,能准确且实时监测患者位置,提高治疗精确度,具有临床应用价值。Objective To investigate the use of optical body surface tracking technology to monitor the effectiveness of breath holding and the repeatability of body position in deep inspiration breath hold radiotherapy for left breast cancer using active breathing control(ABC)technology,so as to ensure the consistency of inspiratory mode of patients in radiotherapy,reduce body position changes,and improve the accuracy of radiotherapy.Methods A total of 23 patients with left side breast cancer who were treated with ABC technology were monitored with Catalyst during the treatment of DIBH position,and the error data of both were recorded respectively with intra-session cone beam computed tomography(CBCT)as the reference standard.The correlation between the two groups of errors and the consistency of the two systems was evaluated by the Pearson method and the Bland-Altman method.The deduction of CBCT registration error value from the monitoring value of optical body surface was defined as the accuracy of Catalyst body surface monitoring.Results The deviation of the errors in the x,y and z translation directions monitored by Catalyst were(0.08±1.04),(1.44±2.15),and(0.45±1.69)mm,respectively.The CBCT registration values were(0.15±1.15),(1.51±2.28),and(0.44±1.81)mm,respectively.The r values of x direction and z direction were 0.60 and 0.77 respectively,showing a strong correlation,while the r-values of y direction were 0.82,showing a very strong correlation.95%CI values in the translation direction of x,y and z axis were[-2.01,1.86]、[-2.69,2.57]、[-2.32,2.34]mm respectively.The monitoring precision of x,y and z directions were(-0.08±0.99),(-0.06±1.34),(0.01±1.19)mm respectively.Conclusion Catalyst can effectively monitor the breath holding status of left breast cancer patients treated with ABC,accurately and real-time monitor the patient’s position,improve the treatment accuracy,and have clinical application value.

关 键 词：CATALYST 光学体表追踪 主动呼吸控制 左侧乳腺癌 放射治疗 

分 类 号：R197.39[医药卫生—卫生事业管理]