不同内固定修复材料治疗跟骨骨折的生物相容性及修复效果研究  

Study on the Biocompatibility and Repair Effect of Different Internal Fixation Materials in the Treatment of Calcaneal Fracture

作　　者：孟琼 李贤[2] 李晓雷 李玉龙 赵倩 马博东 MENG Qiong;LI Xian;LI Xiaolei;LI Yulong;ZHAO Qian;MA Bodong(Hebei College of Traditional Chinese Medicine,Shijiazhuang 050200,China;Department of Orthopedic Surgery,Hebei General Hospital,Shijiazhuang 050000,China)

机构地区：[1]河北中医学院,石家庄050200 [2]河北省人民医院骨科,石家庄050000

出　　处：《临床误诊误治》2023年第7期101-104,133,共5页Clinical Misdiagnosis & Mistherapy

基　　金：河北省健康委员会科研项目(20220902)。

摘　　要：目的 比较不同内固定修复材料治疗跟骨骨折的生物相容性及修复效果。方法 选取2020年5月—2022年5月收治的84例跟骨骨折为研究对象,根据使用内固定修复材料不同分为A组和B组,每组42例。A组选用可吸收螺钉进行内固定,B组选用金属螺钉进行内固定。观察2组围术期指标、并发症、修复效果,以及手术前后影像学指标、红细胞免疫指标[协同肿瘤红细胞免疫花环率(ATER)、直向肿瘤红细胞花环率(DTER)、红细胞C3b受体花环率(RBC-C3bR)]。结果 A组手术时间短于B组,术中出血量少于B组(P<0.01)。2组负重时间、骨折愈合时间比较差异无统计学意义(P>0.05)。术后3个月,2组Gissane角、Bohler角、跟骨高度均高于术前,跟骨宽度低于术前(P<0.05),2组间比较差异无统计学意义(P>0.05)。术后3 d,2组ATER、RBC-C3bR、DTER均低于术前,但A组高于B组(P<0.05)。A组并发症总发生率为4.76%(2/42)低于B组的23.81%(10/42)(P<0.05)。术后3个月,2组修复优良率比较差异无统计学意义(P>0.05)。结论 可吸收螺钉和金属螺钉在跟骨骨折内固定术中效果相当,前者在缩短手术时间、减少术中出血量及并发症、减轻机体红细胞免疫应激方面更具优势。Objective To compare the biocompatibility and repair effect of different internal fixation materials in the treatment of calcaneal fracture.Methods A total of 84 patients with calcaneal fracture treated from May 2020 to May 2022 were selected as the research subjects and divided into group A and group B according to different internal fixation materials,with 42 cases in each group.Absorbable screws were used for internal fixation in group A,and metal screws were used for internal fixation in group B.Perioperative indexes,complications,repair effects,imaging indexes,and red cell immune indexes before and after surgery [synergistic tumor erythrocyte immune garland rate(ATER),direct tumor erythrocyte garland rate(DTER),and red blood cell C3b receptor garland rate(RBC-C3bR)] of the two groups were observed.Results The duration of operation was shorter in group A than in group B,and the amount of intraoperative blood loss was less than that of group B(P<0.01).There was no significant difference in weight-bearing time and fracture healing time between the two groups(P>0.05).At 3 months after surgery,Gissane Angle,Bohler Angle and calcaneus height in the two groups were higher than those before surgery,and calcaneus width was smaller than that before surgery(P<0.05),and there was no statistical significance between the two groups(P>0.05).At 3 d after operation,ATER,RBC-C3bR and DTER in the two groups were lower than those before surgery,which,however,were higher in group A than in group B(P<0.05).The total incidence of complications in group A was 4.76%(2/42),which was lower than that of group B [23.81%(10/42)](P<0.05).At 3 months after operation,there was no significant difference in the excellent and good rate of repair between the two groups(P>0.05).Conclusion Absorbable screw and metal screw have similar effects in internal fixation of calcaneal fracture.The former has more advantages in shortening the duration of operation,reducing intraoperative blood loss and complications,and alleviating red blood cell immune ch

关 键 词：跟骨骨折 骨折固定术 内 可吸收螺钉 金属螺钉 生物相容性材料 并发症 红细胞免疫 围术期 

分 类 号：R683.42[医药卫生—骨科学]