从肾功能和电解质角度探讨中医禁食疗法治疗2型糖尿病的安全性  

Clinical Safety Study of Traditional Chinese Medicine Fasting Therapy in the Treatment of Type 2 Diabetes Mellitus from Kidney Function and Serum Electrolyte

作　　者：胡建国[1] 刘桃丽 陈洪达 张丽[1] 张汀滢 HU Jianguo;LIU Taoli;CHEN Hongda;ZHANG Li;ZHANG Tingying(The Seventh Affiliated Hospital,Sun Yat-sen University,Shenzhen 518000,Guangdong,China)

机构地区：[1]中山大学附属第七医院,广东深圳518000

出　　处：《实用中医内科杂志》2023年第12期27-30,共4页Journal of Practical Traditional Chinese Internal Medicine

基　　金：国家自然科学基金项目(81874498);广州市科技计划项目(201903010044);深圳市卫生系统科研项目(SZLY2018002)。

摘　　要：目的从肾功能和电解质角度回顾性研究中医禁食疗法治疗2型糖尿病(Type 2 Diabetes Mellitus,T2DM)的安全性。方法从既往出院患者中,筛选出合乎要求的45例T2DM患者,比较T2DM患者在进行中医禁食疗法前后在肾功能和电解质检测指标的变化情况。结果45例T2DM患者中,进行中医禁食疗法治疗后,在空腹血糖、体质量、体质指数、尿素、胱抑素C、血清钠离子、血清氯离子等方面相较于治疗前有明显下降,在肌酐、尿酸、血清钾离子等方面相较于治疗前有上升态势,而在二氧化碳方面相较于治疗前无显著性改变。结论中医禁食疗法治疗T2DM安全有效。Objective The safety of traditional Chinese medicine fasting therapy for the treatment of type 2 diabetes mellitus(T2DM)from the perspectives of kidney function and serum electrolyte was discussed retrospectively.Methods From previously discharged patients,45 eligible T2DM patients were screened and compared the changes in kidney function and serum electrolyte indicators before and after traditional Chinese medicine fasting therapy.Results Among the 45 T2DM patients,there were obvious declines in fasting plasma glucose,body weight,body mass index(BMI),serum urea,serum cystatin C,serum natrium and serum chlorine.There were increasing trends in serum creatinine,serum uric acid and serum kalium compared with those before treatment and no significant change in serum carbon dioxide compared with those before treatment.Conclusions Traditional Chinese medicine fasting therapy is safe and effective in the treatment of T2DM.

关 键 词：肾功能 电解质 中医禁食疗法 2型糖尿病 安全性 

分 类 号：R259[医药卫生—中西医结合]