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作 者:李超[1] 张冬梅[2] 赵京霞[3] 耿子涵 陈澈 熊俊[6] 何怡瀚 王蕊 毕明刚[8] LI Chao;ZHANG Dongmei;ZHAO Jingxia;GENG Zihan;CHEN Che;XIONG Jun;HE Yihan;WANG Rui;BI Minggang(Innovative Research Institute of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250355,China;Key Laboratory of Chinese Internal Medicine of Ministry of Education,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Beijing Key Laboratory of Clinic and Basic Research with Traditional Chinese Medicine on Psoriasis,Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China;Institute ofChinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;School of Chinese Medicine,Ningxia Medical University,Yinchuan 750004,China;Department of Acupuncture and Moxibustion,Affiliated Hospital ofJiangxi University of Chinese Medicine,Nanchang 330006,China;Department of Oncology,Second Affiliated Hospital ofGuangzhou University of Chinese Medicine,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou 510120,China;National Natural Science Foundation of China,Beijing 100085,China)
机构地区:[1]山东中医药大学中医药创新研究院,济南250355 [2]北京中医药大学东直门医院,中医内科学教育部重点实验室,北京100700 [3]首都医科大学附属北京中医医院,银屑病中医临床基础研究北京市重点实验室,北京100010 [4]中国中医科学院中药研究所,北京100700 [5]宁夏医科大学中医学院,银川750004 [6]江西中医药大学附属医院针灸科,南昌330006 [7]广州中医药大学第二附属医院/广州省中医院肿瘤科,广州510120 [8]国家自然科学基金委员会,北京100085
出 处:《天津中医药》2024年第1期130-136,共7页Tianjin Journal of Traditional Chinese Medicine
摘 要:系统梳理分析2022年国家自然科学基金心血管领域中、西医学面上项目、青年科学基金项目和地区科学基金项目3类常规项目的申请和资助情况、所涉及主要病种、研究热点和研究思路。结果显示,两个领域研究的主要病种相似,研究热点也基本一致。均以动脉粥样硬化、冠心病、心力衰竭、高血压、继发性心肌损伤和心律失常为主,主要开展表观遗传学、外泌体、细胞焦亡或铁死亡、细胞自噬、肠道微生物群以及线粒体功能方面的研究,思路呈现多样化的特点。但西医心血管领域的病种更为广泛,还包括心脏移植等中医心血管领域不涉及的病种。在科学问题导向和研究内容方面,中医心血管领域要求在中医药理论的指导下,以解决中医学科的关键科学问题为导向,体现中医药的特色。此外,研究热点只是探索科学问题的技术手段,应深入凝练科学问题,避免盲目追求结合研究热点反而缺乏了创新性思想和科学依据,鼓励原创性基础研究。Systematically review and analyze the application and funding status,main diseases involved,research hotspots,and research ideas of three types of conventional projects in the cardiovascular field of the National Natural Science Foundation of China,Western Medicine General Project,Youth Science Foundation Project,and Regional Science Foundation Project in 2022.The results show that the main diseases studied in the two fields are similar,and the research hotspots are basically the same.They mainly focus on atherosclerosis,coronary heart disease,heart failure,hypertension,secondary myocardial injury and arrhythmia,and mainly carry out research on epigenetics,exosomes,pyroptosis or iron death,autophagy,intestinal microbiota,and mitochondrial function,showing diversified characteristics of thinking.However,the cardiovascular field of Western medicine has a wider range of diseases,including diseases not covered by traditional Chinese medicine such as heart transplantation.In terms of scientific problem orientation and research content,the field of traditional Chinese medicine cardiovascular disease requires that under the guidance of traditional Chinese medicine theory,the key scientific problems in the field of traditional Chinese medicine should be solved as the guidance,reflecting the characteristics of traditional Chinese medicine.In addition,research hotspots are only technical means to explore scientific issues,and scientific problems should be deeply condensed to avoid blindly pursuing the combination of research hotspots,which may lack innovative ideas and scientific basis.Original basic research should be encouraged.
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