1995—2022年四川省艾滋病病毒感染儿童接受抗病毒治疗情况及影响因素分析  

Analysis of antiretroviral therapy for children with HIV infections and its influencing factors in Sichuan Province from 1995 to 2022

作　　者：李菊梅 任建华 高鑫 马瑞 杨薇[1] 袁风顺 喻航[1] 杨一挥[1] LI Jumei;REN Jianhua;GAO Xin;MA Rui;YANG Wei;YUAN Fengshun;YU Hang;YANG Yihui(Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China)

机构地区：[1]四川省疾病预防控制中心,成都610041

出　　处：《寄生虫病与感染性疾病》2023年第4期198-202,214,共6页Parasitoses and Infectious Diseases

基　　金：四川省疾病预防控制中心自立科研课题(项目编号:ZX202015);四川省儿童保护与发展中心(项目编号:ETBH2022-ZD001)。

摘　　要：目的 了解四川省儿童艾滋病患者接受抗病毒治疗情况及影响因素,为进一步提升儿童患者生存质量提供依据。方法 通过中国艾滋病综合防治信息系统获得1995—2022年四川省累计确证检测年龄<15岁的艾滋病患者,以是否开展抗病毒治疗为研究结局,收集患者的年龄、性别、确证时间、流动、失访等情况,采用Logistic回归方法进行单因素和多因素分析,检验水准α=0.05。结果 1995—2022年四川省累计确证儿童艾滋病患者4 337例,抗病毒治疗覆盖率为91.01%。多因素分析结果显示:3~9岁确证、10~14岁确证、疾病名称为AIDS、现住址为凉山、2018年确证、2019年确证、2020年确证、2021年确证、2022年确证和无症状是儿童患者接受抗病毒治疗的促进因素,输血/注射传播是儿童患者接受抗病毒治疗的阻碍因素。结论 四川省儿童艾滋病患者抗病毒治疗覆盖率较高。应加强对小年龄组、凉山州以外市(州)儿童的关注。持续推动儿童患者抗病毒治疗覆盖率及质量,为2030终结艾滋病奠定基础。Objective To understand the antiretroviral therapy and influencing factors for children with HIV/AIDS in Sichuan Province,and to provide a basis for further improving the quality of life for affected children.Methods By accessing the China Comprehensive AIDS Prevention and Control Information System,datas on children under the age of 15 who were confirmed to have HIV/AIDS in Sichuan Province from 1995 to 2022 were obtained.Using the initiation of antiretroviral therapy as the study outcome,patients'information were collected,such as age,gender,diagnosis time,migration,loss to follow-up and so on.Univariate and multivariate Logistic regression analysises were conducted with a significance levelα=0.05.Results From 1995 to 2022,a total of 4337children with confirmed HIV/AIDS were reported in Sichuan Province,with an antiretroviral therapy coverage rate of 91.01%.Multivariate analysis results showed that children patients aged 3-9,aged10-14,with a disease name of AIDS,residing in Liangshan,diagnosed in 2018,2019,2020,2021,and 2022,and being asymptomatic were facilitating factors for receiving antiretroviral therapy.Blood transfusion/injection transmission was a hindering factor for children patients receiving antiretroviral therapy.Conclusions The antiretroviral therapy coverage rate for children with HIV/AIDS in Sichuan Province is relatively high.Efforts should be strengthened to focus on younger children and those outside Liangshan Region.Continuing to promote antiretroviral therapy coverage and quality for children is essential for laying the foundation to end the HIV/AIDS epidemic by 2030.

关 键 词：艾滋病 儿童 抗病毒治疗 

分 类 号：R512.91[医药卫生—内科学]