儿童扁桃体腺样体肥大组织淋巴细胞改变的研究进展  

Advances in the changes of lymphocytes in pediatric adenoid and tonsil hypertrophy

作　　者：朱雅欣 刘峰[1] 关建[1] 殷善开[1] ZHU Yaxin;LIU Feng;GUAN Jian;YIN Shankai(Department of Otolaryngology&Head and Neck Surgery,Shanghai Jiao Tong University School of Medicine Affiliated Sixth People′s Hospital,Shanghai 200233,China)

机构地区：[1]上海交通大学医学院附属第六人民医院耳鼻咽喉头颈外科,上海200233

出　　处：《山东大学耳鼻喉眼学报》2023年第6期62-67,共6页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：国家自然科学基金项目(81971240)。

摘　　要：扁桃体腺样体肥大是儿童阻塞性睡眠呼吸暂停最常见的病因,由于缺乏安全有效的内科学治疗手段,对于其发病机制的探索越来越受到人们的关注。近年来许多国内外的研究表明肥大扁桃体腺样体组织中过度的炎症反应和生发中心反应与淋巴细胞组成和功能的异常相关,论文将对此进行综述。Adenotonsillar hypertrophy is the most common cause of pediatric obstructive sleep apnea.The immunopathologic findings of adenotonsillar hypertrophy have become a field of interest due to the lack of a safe and effective medical treatment.Recent local and foreign studies have shown that the excessive inflammatory response and germinal center response in hypertrophied adenotonsillar tissue are related to the abnormal composition and function of the lymphocytes.These characteristics will be described further in this review.

关 键 词：扁桃体腺样体肥大 阻塞性睡眠呼吸暂停 T细胞 B细胞 固有淋巴样细胞 

分 类 号：R766.3[医药卫生—耳鼻咽喉科]