虫媒病毒感染传播及跨界免疫适应机制  

Infection, Transmission, and Cross-kingdom Immune Adaption of Arboviruses

作　　者：康乐[1] 李毅[2] 程功 崔峰[1] 张莉莉[4] 张晓明 吴燕 赵婉[1] 霍岩[4] 杜和山 薛岚[6] 于振良[6] Le Kang;Yi Li;Gong Cheng;Feng Cui;Lili Zhang;Xiaoming Zhang;Yan Wu;Wan Zhao;Yan Huo;Heshan Du;Lan Xue;Zhenliang Yu(Institute of Zoology,Chinese Academy of Sciences,Beijing 100101;School of Life Sciences,Peking University,Beijing 100871;School of Medicine,Tsinghua University,Beijing 100084;Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101;School of Basic Medical Sciences,Capital Medical University,Beijing 100069;Department of Life Sciences,National Natural Science Foundation of China,Beijing 100085)

机构地区：[1]中国科学院动物研究所,北京100101 [2]北京大学生命科学学院,北京100871 [3]清华大学医学院,北京100084 [4]中国科学院微生物研究所,北京100101 [5]首都医科大学基础医学院,北京100069 [6]国家自然科学基金委员会生命科学部,北京100085

出　　处：《中国科学基金》2023年第6期1011-1020,共10页Bulletin of National Natural Science Foundation of China

摘　　要：基于第323期“双清论坛”,本文在介绍虫媒病领域的研究背景下,从媒介生物学、虫媒病毒学和病毒—虫媒—宿主互作三个方面梳理了我国在医学、动物及植物虫媒病毒领域的研究进展,涉及病毒感染媒介的分子机制、虫媒病毒的免疫互作机制、病毒跨界传播机制以及虫媒病健康绿色防控的新方法,凝练出该领域亟需解决的关键科学问题,提出我国未来5~10年虫媒病领域的发展目标。Based on the 323rd Shuangqing Forum,we review the research progress on arboviruses for medicine,animals and plants in China,including vector biology,arbovirology,and virus-vector-host interaction.This review discusses the mechanisms of viral infection,immune interaction and crosskingdom transmission,and new healthy and green methods for prevention and control of vector-borne diseases.The key scientific questions in the area of vector-borne diseases and developmental objectives in the next 5-10 years are summarized and brought forward.

关 键 词：虫媒病 媒介生物学 虫媒病毒学 病毒—虫媒—宿主互作 

分 类 号：R53[医药卫生—内科学]