代谢手术对肥胖女性生殖内分泌系统疾病影响的研究进展  

Research progress on the impact of metabolic surgery on reproductive endocrine system diseases in obese women

作　　者：蔡美丽 张曼娜[1] 曲伸[1] Cai Meili;Zhang Manna;Qu Shen(Department of Endocrinology&Metabolism,Shanghai Tenth People's Hospital,Tongji University School of Medicine,Shanghai 200072,China)

机构地区：[1]同济大学附属第十人民医院内分泌代谢科,上海200072

出　　处：《国际内分泌代谢杂志》2023年第6期469-472,共4页International Journal of Endocrinology and Metabolism

基　　金：国家自然科学基金项目(81601269, 82170861, 81970677);上海市申康医院发展中心临床研究计划(SHDC2020CR1017B)。

摘　　要：全球肥胖患病率逐年激增, 肥胖已成为全球性的公共卫生挑战。肥胖所带来的危害巨大, 除了显著增加各种代谢紊乱性疾病的风险外, 对生殖内分泌系统亦有多种负面影响。代谢手术是目前公认的治疗肥胖最有效、最长期的减重方法, 在肥胖相关代谢异常疾病方面已显示出其独特的优势与疗效, 但代谢手术对肥胖女性生殖内分泌系统疾病影响的研究关注较少且存在异质性。本综述将系统回顾代谢手术对肥胖女性生殖内分泌系统疾病影响的研究进展, 旨在深入理解代谢手术在女性生殖健康中的作用及相关机制, 为临床医生诊疗提供重要的循证医学证据。The global prevalence of obesity is steadily increasing year by year,and obesity has now emerged as a global public health challenge.Obesity carries significant hazards,not only significantly increasing the risk of various metabolic disorders but also exerting multiple adverse effects on the reproductive endocrine system.Bariatric surgery is presently recognized as the most effective and durable method for treating obesity,demonstrating its unique advantages and therapeutic efficacy in addressing obesity-related metabolic disorders.However,research into the impact of metabolic surgery on reproductive endocrine system disorders in obese women has been relatively scarce and characterized by heterogeneity.This comprehensive review aims to systematically examine the progress in research regarding the effects of bariatric surgery on reproductive endocrine system disorders in obese women.Its primary objective is to gain a deeper understanding of the role of bariatric surgery in female reproductive health and the associated mechanisms,ultimately providing crucial evidence-based guidance for clinical practitioners.

关 键 词：代谢手术 肥胖 生殖内分泌系统疾病 多囊卵巢综合征 

分 类 号：R589.2[医药卫生—内分泌]