瓜蒌薤白汤合养心活血汤对慢性心力衰竭患者心功能和血脂代谢指标的影响研究  

The Influence of the Decoction on Cardiac Function and Blood Lipid Metabolism in Patients with Chronic Heart Failure

作　　者：陈定宇 CHEN Ding-yu(Internal Department of Traditional Chinese Medicine,Fuzhou 8th Hospital,Fuzhou 350013,Fujian Province,China)

机构地区：[1]福州市第八医院中医内科,福建福州350013

出　　处：《罕少疾病杂志》2024年第1期60-61,70,共3页Journal of Rare and Uncommon Diseases

基　　金：福建省自然科学基金项目计划(2018J01190)。

摘　　要：目的研究瓜蒌薤白汤+养心活血汤运用于慢性心力衰竭患者中的价值。方法选择我院2022年1月-2022年6月纳入的慢性心力衰竭患者70例,以随机排列法进行分组,各35例,研究组服用瓜蒌薤白汤+养心活血汤,对照组使用常规治疗,比较两组服药前后的症状积分、左室收缩及左室舒张末期内径(LVESD、LVEDD)、左心射血分数(LVEF)、高密度及低密度脂蛋白(HDL-C、LDL-C)、总胆固醇(TC)、甘油三酯(TG),统计两组不良反应(皮疹、头晕、恶心呕吐)情况,比较两组服药结果。结果服药前两组症状积分并无差异(P>0.05),服药后研究组胸闷气短、胸痛、喘促、下肢水肿、畏寒肢冷积分小于对照组(P<0.05)。服药前两组心功能并无差异(P>0.05),服药后研究组LVESD、LVEDD小于对照组,但LVEF大于对照组(P<0.05)。服药前两组血脂代谢指标并无差异(P>0.05),服药后研究组HDL-C大于对照组,但TC、LDL-C、TG小于对照组(P<0.05)。研究组不良反应5.71%少于对照组28.57%(P<0.05)。结论瓜蒌薤白汤+养心活血汤的效果更突出,能够增强心功能,改善血脂代谢情况,促进症状快速减轻,不良反应少,值得推广。Objective To study the value of the decoction+Yangxin decoction in patients with chronic heart failure.Methods 70 patients with chronic heart failure enrolled in our hospital from January 2022 to June 2022 were selected and grouped by random arrangement method,with 35 patients in each group.Research group took,gualou macrostebai soup+Yangxin blood circulation soup,and the control group used the conventional treatment,compare the symptom integral,LV systolic and LV end-diastolic internal diameter(LVESD,LVEDD),left heart ejection fraction(LVEF),high density and low density lipoprotein(HDL-C,LDL-C),total cholesterol(TC),triglycerides(TG),Two groups of adverse reactions(rash,dizziness,nausea and vomiting),Compare the medication results between the two groups.Results There was no difference in the two symptom points before medication(P>0.05),and the score points of chest tightness,chest pain,asthma,lower limb edema,and cold fear were less than that of the control group(P<0.05).There was no difference in cardiac function between the two groups before medication(P>0.05).After medication,LVESD and LVEDD in the study group were less than the control group,but LVEF was greater than the control group(P<0.05).There was no difference in lipid metabolism between the two groups before medication(P>0.05).After medication,HDL-C HDL-C in the study group was greater than the control group,but TC,LDL-C and TG were less than the control group(P<0.05).Adverse reactions in the study group were 5.71%less than 28.57%in the control group(P<0.05).Conclusion The effect of gujiao macrowhite soup+Yangxin blood circulation soup is more prominent,which can enhance the heart function,improve the metabolism of blood lipid,promote the rapid reduction of symptoms and less adverse reactions,which is worth promoting.

关 键 词：心功能 瓜蒌薤白汤 慢性心力衰竭 养心活血汤 

分 类 号：R541.6[医药卫生—心血管疾病]